The Cholinergic Hypothesis: An Introduction to the Hypothesis and a Short History

Joseph I. Friedman, Isabella Kanellopoulou, Vladan Novakovic

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

2 Scopus citations
Original languageEnglish
Title of host publicationTargets and Emerging Therapies for Schizophrenia
PublisherJohn Wiley and Sons
Number of pages24
ISBN (Print)9780470322826
StatePublished - 24 Jun 2012


  • ACh subtypes in normal cognitive, and cholinergic system of the brain
  • AChE inhibitors and cholinergic increase, galantamine in nAChR response
  • Cholinergic hypothesis, CNS cholinergic disruptions in schizophrenia impairment
  • Memory and Ach, central cholinergic neurotransmission and cognition
  • NAChRs, ligand-gated, in membrane depolarization/neuronal excitation

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