The cellular neurobiology of depression

Husseini K. Manji; Wayne C. Drevets; Dennis S. Charney

doi:10.1038/87865

The cellular neurobiology of depression

Husseini K. Manji, Wayne C. Drevets, Dennis S. Charney

Research output: Contribution to journal › Review article › peer-review

178 Scopus citations

Abstract

Major depressive disorders, long considered to be of neurochemical origin, have recently been associated with impairments in signaling pathways that regulate neuroplasticity and cell survival. Agents designed to directly target molecules in these pathways may hold promise as new therapeutics for depression.

Original language	English
Pages (from-to)	541-547
Number of pages	7
Journal	Nature Medicine
Volume	7
Issue number	5
DOIs	https://doi.org/10.1038/87865
State	Published - May 2001
Externally published	Yes

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title = "The cellular neurobiology of depression",

abstract = "Major depressive disorders, long considered to be of neurochemical origin, have recently been associated with impairments in signaling pathways that regulate neuroplasticity and cell survival. Agents designed to directly target molecules in these pathways may hold promise as new therapeutics for depression.",

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The cellular neurobiology of depression

Abstract

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