The carbapenem-resistant Enterobacteriaceae score: A bedside score to rule out infection with carbapenem-resistant Enterobacteriaceae among hospitalized patients

Emily T. Martin, Ryan Tansek, Vicki Collins, Kayoko Hayakawa, Odaliz Abreu-Lanfranco, Teena Chopra, Paul R. Lephart, Jason M. Pogue, Keith S. Kaye, Dror Marchaim

Research output: Contribution to journalArticlepeer-review

19 Scopus citations

Abstract

Patients infected with carbapenem-resistant Enterobacteriaceae often experience delays in initiation of appropriate antimicrobial therapy and increased mortality. A score was developed to differentiate bloodstream infections caused by carbapenem-resistant Enterobacteriaceae (16 patients) versus extended-spectrum β-lactamase-producing Enterobacteriaceae (166 patients). A score of ≥32 demonstrated high area under the curve of 0.80 (95% confidence interval: 0.68-0.92) and a negative predictive value of 97%.

Original languageEnglish
Pages (from-to)180-182
Number of pages3
JournalAmerican Journal of Infection Control
Volume41
Issue number2
DOIs
StatePublished - Feb 2013
Externally publishedYes

Keywords

  • CRE
  • Carbapenem-resistant Enterobacteriaceae
  • Colistin
  • ESBL
  • Extended-spectrum β-lactamase
  • Klebsiella pneumoniae carbapenemase
  • Time to effective therapy

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