The beauty of seeing the real thing: BMP heterodimer detection in vivo reveals dimer composition and activity

Giovanna M. Collu; Marek Mlodzik

doi:10.1016/j.devcel.2023.03.022

The beauty of seeing the real thing: BMP heterodimer detection in vivo reveals dimer composition and activity

Research output: Contribution to journal › Comment/debate

Abstract

BMP family ligands can direct cells to divide, differentiate, or die, depending on cell context and specific hetero- or homodimer combinations. In this issue of Developmental Cell, Bauer et al. detect endogenous Drosophila ligand dimers in situ and show that BMP dimer composition affects both signaling range and activity.

Original language	English
Pages (from-to)	633-634
Number of pages	2
Journal	Developmental Cell
Volume	58
Issue number	8
DOIs	https://doi.org/10.1016/j.devcel.2023.03.022
State	Published - 24 Apr 2023

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title = "The beauty of seeing the real thing: BMP heterodimer detection in vivo reveals dimer composition and activity",

abstract = "BMP family ligands can direct cells to divide, differentiate, or die, depending on cell context and specific hetero- or homodimer combinations. In this issue of Developmental Cell, Bauer et al. detect endogenous Drosophila ligand dimers in situ and show that BMP dimer composition affects both signaling range and activity.",

author = "Collu, {Giovanna M.} and Marek Mlodzik",

note = "Publisher Copyright: {\textcopyright} 2023 Elsevier Inc.",

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language = "English",

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T2 - BMP heterodimer detection in vivo reveals dimer composition and activity

AU - Collu, Giovanna M.

AU - Mlodzik, Marek

PY - 2023/4/24

Y1 - 2023/4/24

N2 - BMP family ligands can direct cells to divide, differentiate, or die, depending on cell context and specific hetero- or homodimer combinations. In this issue of Developmental Cell, Bauer et al. detect endogenous Drosophila ligand dimers in situ and show that BMP dimer composition affects both signaling range and activity.

AB - BMP family ligands can direct cells to divide, differentiate, or die, depending on cell context and specific hetero- or homodimer combinations. In this issue of Developmental Cell, Bauer et al. detect endogenous Drosophila ligand dimers in situ and show that BMP dimer composition affects both signaling range and activity.

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U2 - 10.1016/j.devcel.2023.03.022

DO - 10.1016/j.devcel.2023.03.022

M3 - Comment/debate

AN - SCOPUS:85152554935

SN - 1534-5807

VL - 58

SP - 633

EP - 634

JO - Developmental Cell

JF - Developmental Cell

IS - 8

ER -

The beauty of seeing the real thing: BMP heterodimer detection in vivo reveals dimer composition and activity

Abstract

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