The B cell antigen CD75 Is a cell surface sialyltransferase

Ivan Stamenkovic; Hans Christian Asheim; Arne Deggerdal; Heidi Kiil Blomhoff; Erlend B. Smeland; Steinar Funderud

The B cell antigen CD75 Is a cell surface sialyltransferase

Ivan Stamenkovic
, Hans Christian Asheim
, Arne Deggerdal
, Heidi Kiil Blomhoff
, Erlend B. Smeland
, Steinar Funderud

Research output: Contribution to journal › Article › peer-review

62 Scopus citations

Abstract

In this work we have isolated a cDNA clone encoding the B cell antigen CD75. The amino acid sequence of CD75 is shown to be identical to that of human α2,6 sialyltransferase, believed to be primarily associated with the Golgi complex. This is the first demonstration of cell surface expression of sialyltransferase which, in B cells, may play an important role in intercellular adhesion and antigen presentation events.

Original language	English
Pages (from-to)	641-643
Number of pages	3
Journal	Journal of Experimental Medicine
Volume	172
Issue number	2
State	Published - 1 Aug 1990
Externally published	Yes

Cite this

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title = "The B cell antigen CD75 Is a cell surface sialyltransferase",

abstract = "In this work we have isolated a cDNA clone encoding the B cell antigen CD75. The amino acid sequence of CD75 is shown to be identical to that of human α2,6 sialyltransferase, believed to be primarily associated with the Golgi complex. This is the first demonstration of cell surface expression of sialyltransferase which, in B cells, may play an important role in intercellular adhesion and antigen presentation events.",

author = "Ivan Stamenkovic and Asheim, \{Hans Christian\} and Arne Deggerdal and Blomhoff, \{Heidi Kiil\} and Smeland, \{Erlend B.\} and Steinar Funderud",

year = "1990",

month = aug,

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language = "English",

volume = "172",

pages = "641--643",

journal = "Journal of Experimental Medicine",

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T1 - The B cell antigen CD75 Is a cell surface sialyltransferase

AU - Stamenkovic, Ivan

AU - Asheim, Hans Christian

AU - Deggerdal, Arne

AU - Blomhoff, Heidi Kiil

AU - Smeland, Erlend B.

AU - Funderud, Steinar

PY - 1990/8/1

Y1 - 1990/8/1

N2 - In this work we have isolated a cDNA clone encoding the B cell antigen CD75. The amino acid sequence of CD75 is shown to be identical to that of human α2,6 sialyltransferase, believed to be primarily associated with the Golgi complex. This is the first demonstration of cell surface expression of sialyltransferase which, in B cells, may play an important role in intercellular adhesion and antigen presentation events.

AB - In this work we have isolated a cDNA clone encoding the B cell antigen CD75. The amino acid sequence of CD75 is shown to be identical to that of human α2,6 sialyltransferase, believed to be primarily associated with the Golgi complex. This is the first demonstration of cell surface expression of sialyltransferase which, in B cells, may play an important role in intercellular adhesion and antigen presentation events.

UR - https://www.scopus.com/pages/publications/0025182384

M3 - Article

C2 - 2373995

AN - SCOPUS:0025182384

SN - 0022-1007

VL - 172

SP - 641

EP - 643

JO - Journal of Experimental Medicine

JF - Journal of Experimental Medicine

IS - 2

ER -

The B cell antigen CD75 Is a cell surface sialyltransferase

Abstract

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