TY - JOUR
T1 - The B cell antigen CD75 Is a cell surface sialyltransferase
AU - Stamenkovic, Ivan
AU - Asheim, Hans Christian
AU - Deggerdal, Arne
AU - Blomhoff, Heidi Kiil
AU - Smeland, Erlend B.
AU - Funderud, Steinar
PY - 1990/8/1
Y1 - 1990/8/1
N2 - In this work we have isolated a cDNA clone encoding the B cell antigen CD75. The amino acid sequence of CD75 is shown to be identical to that of human α2,6 sialyltransferase, believed to be primarily associated with the Golgi complex. This is the first demonstration of cell surface expression of sialyltransferase which, in B cells, may play an important role in intercellular adhesion and antigen presentation events.
AB - In this work we have isolated a cDNA clone encoding the B cell antigen CD75. The amino acid sequence of CD75 is shown to be identical to that of human α2,6 sialyltransferase, believed to be primarily associated with the Golgi complex. This is the first demonstration of cell surface expression of sialyltransferase which, in B cells, may play an important role in intercellular adhesion and antigen presentation events.
UR - https://www.scopus.com/pages/publications/0025182384
M3 - Article
C2 - 2373995
AN - SCOPUS:0025182384
SN - 0022-1007
VL - 172
SP - 641
EP - 643
JO - Journal of Experimental Medicine
JF - Journal of Experimental Medicine
IS - 2
ER -