The autonomic orienting response and CT scan findings in schizophrenia

David B. Schnur, Alvin S. Bernstein, Sukdeb Mukherjee, John Loh, Gustav Degreef, James Reidel

Research output: Contribution to journalArticlepeer-review

19 Scopus citations

Abstract

CT scan measures of prefrontal sulcal prominence, parieto-occipital sulcal prominence, ventricle-brain ratio (VBR), and third ventricle width (TVW) were examined in 24 schizophrenic patients who were grouped on the basis of their autonomic orienting response (OR) status. A two-component definition of the OR was used that required concordance across both electrodermal and finger pulse volume components for response status assignment. The nine OR responders had significantly greater TVW than the 15 OR nonresponders. Although OR responders had higher values also on the other CT scan measures, these differences were not significant. These findings are consistent with the possibility that OR responsiveness and nonresponsiveness are related to different pathological dimensions of schizophrenia.

Original languageEnglish
Pages (from-to)449-455
Number of pages7
JournalSchizophrenia Research
Volume2
Issue number6
DOIs
StatePublished - 1989
Externally publishedYes

Keywords

  • Autonomic orienting response
  • CT scan

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