The association between body mass index and gastroesophageal reflux disease in the World Trade Center Health Program General Responder Cohort

Nikolina Icitovic; Lynn C. Onyebeke; Sylvan Wallenstein; Christopher R. Dasaro; Denise Harrison; Jieying Jiang; Julia R. Kaplan; Roberto G. Lucchini; Benjamin J. Luft; Jacqueline M. Moline; Lakshmi Pendem; Moshe Shapiro; Iris G. Udasin; Andrew C. Todd; Susan L. Teitelbaum

doi:10.1002/ajim.22637

The association between body mass index and gastroesophageal reflux disease in the World Trade Center Health Program General Responder Cohort

Nikolina Icitovic, Lynn C. Onyebeke, Sylvan Wallenstein, Christopher R. Dasaro, Denise Harrison, Jieying Jiang, Julia R. Kaplan, Roberto G. Lucchini, Benjamin J. Luft, Jacqueline M. Moline, Lakshmi Pendem, Moshe Shapiro, Iris G. Udasin, Andrew C. Todd, Susan L. Teitelbaum

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

Background: There is increasing concern about the obesity epidemic in the United States. Obesity is a potential risk factor for a number of chronic diseases, including gastroesophageal reflux disease (GERD). This analysis examined whether body mass index (BMI) was associated with physician-diagnosed GERD in World Trade Center (WTC) general responders. Methods: 19,819 WTC general responders were included in the study. Cox proportional hazards regression models were used to compare time to GERD diagnosis among three BMI groups (normal (<25 kg/m²), overweight (≥25 and <30 kg/m²), and obese (≥30 kg/m²)). Results: Among the responders, 43% were overweight and 42% were obese. The hazard ratio for normal versus overweight was 0.81 (95% Confidence Interval (CI), 0.75–0.88); normal versus obese 0.71 (95%CI, 0.66, 0.77); and overweight versus obese 0.88 (95%CI, 0.83–0.92). Conclusion: GERD diagnoses rates were higher in overweight and obese WTC responders. Am. J. Ind. Med. 59:761–766, 2016.

Original language	English
Pages (from-to)	761-766
Number of pages	6
Journal	American Journal of Industrial Medicine
Volume	59
Issue number	9
DOIs	https://doi.org/10.1002/ajim.22637
State	Published - 1 Sep 2016

Keywords

9/11
BMI
GERD
World Trade Center

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10.1002/ajim.22637

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Icitovic, N., Onyebeke, L. C., Wallenstein, S., Dasaro, C. R., Harrison, D., Jiang, J., Kaplan, J. R., Lucchini, R. G., Luft, B. J., Moline, J. M., Pendem, L., Shapiro, M., Udasin, I. G., Todd, A. C., & Teitelbaum, S. L. (2016). The association between body mass index and gastroesophageal reflux disease in the World Trade Center Health Program General Responder Cohort. American Journal of Industrial Medicine, 59(9), 761-766. https://doi.org/10.1002/ajim.22637

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title = "The association between body mass index and gastroesophageal reflux disease in the World Trade Center Health Program General Responder Cohort",

abstract = "Background: There is increasing concern about the obesity epidemic in the United States. Obesity is a potential risk factor for a number of chronic diseases, including gastroesophageal reflux disease (GERD). This analysis examined whether body mass index (BMI) was associated with physician-diagnosed GERD in World Trade Center (WTC) general responders. Methods: 19,819 WTC general responders were included in the study. Cox proportional hazards regression models were used to compare time to GERD diagnosis among three BMI groups (normal (<25 kg/m2), overweight (≥25 and <30 kg/m2), and obese (≥30 kg/m2)). Results: Among the responders, 43% were overweight and 42% were obese. The hazard ratio for normal versus overweight was 0.81 (95% Confidence Interval (CI), 0.75–0.88); normal versus obese 0.71 (95%CI, 0.66, 0.77); and overweight versus obese 0.88 (95%CI, 0.83–0.92). Conclusion: GERD diagnoses rates were higher in overweight and obese WTC responders. Am. J. Ind. Med. 59:761–766, 2016.",

keywords = "9/11, BMI, GERD, World Trade Center",

author = "Nikolina Icitovic and Onyebeke, {Lynn C.} and Sylvan Wallenstein and Dasaro, {Christopher R.} and Denise Harrison and Jieying Jiang and Kaplan, {Julia R.} and Lucchini, {Roberto G.} and Luft, {Benjamin J.} and Moline, {Jacqueline M.} and Lakshmi Pendem and Moshe Shapiro and Udasin, {Iris G.} and Todd, {Andrew C.} and Teitelbaum, {Susan L.}",

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year = "2016",

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doi = "10.1002/ajim.22637",

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Icitovic, N, Onyebeke, LC, Wallenstein, S, Dasaro, CR, Harrison, D, Jiang, J, Kaplan, JR, Lucchini, RG, Luft, BJ, Moline, JM, Pendem, L, Shapiro, M, Udasin, IG, Todd, AC & Teitelbaum, SL 2016, 'The association between body mass index and gastroesophageal reflux disease in the World Trade Center Health Program General Responder Cohort', American Journal of Industrial Medicine, vol. 59, no. 9, pp. 761-766. https://doi.org/10.1002/ajim.22637

TY - JOUR

T1 - The association between body mass index and gastroesophageal reflux disease in the World Trade Center Health Program General Responder Cohort

AU - Icitovic, Nikolina

AU - Onyebeke, Lynn C.

AU - Wallenstein, Sylvan

AU - Dasaro, Christopher R.

AU - Harrison, Denise

AU - Jiang, Jieying

AU - Kaplan, Julia R.

AU - Lucchini, Roberto G.

AU - Luft, Benjamin J.

AU - Moline, Jacqueline M.

AU - Pendem, Lakshmi

AU - Shapiro, Moshe

AU - Udasin, Iris G.

AU - Todd, Andrew C.

AU - Teitelbaum, Susan L.

PY - 2016/9/1

Y1 - 2016/9/1

N2 - Background: There is increasing concern about the obesity epidemic in the United States. Obesity is a potential risk factor for a number of chronic diseases, including gastroesophageal reflux disease (GERD). This analysis examined whether body mass index (BMI) was associated with physician-diagnosed GERD in World Trade Center (WTC) general responders. Methods: 19,819 WTC general responders were included in the study. Cox proportional hazards regression models were used to compare time to GERD diagnosis among three BMI groups (normal (<25 kg/m2), overweight (≥25 and <30 kg/m2), and obese (≥30 kg/m2)). Results: Among the responders, 43% were overweight and 42% were obese. The hazard ratio for normal versus overweight was 0.81 (95% Confidence Interval (CI), 0.75–0.88); normal versus obese 0.71 (95%CI, 0.66, 0.77); and overweight versus obese 0.88 (95%CI, 0.83–0.92). Conclusion: GERD diagnoses rates were higher in overweight and obese WTC responders. Am. J. Ind. Med. 59:761–766, 2016.

AB - Background: There is increasing concern about the obesity epidemic in the United States. Obesity is a potential risk factor for a number of chronic diseases, including gastroesophageal reflux disease (GERD). This analysis examined whether body mass index (BMI) was associated with physician-diagnosed GERD in World Trade Center (WTC) general responders. Methods: 19,819 WTC general responders were included in the study. Cox proportional hazards regression models were used to compare time to GERD diagnosis among three BMI groups (normal (<25 kg/m2), overweight (≥25 and <30 kg/m2), and obese (≥30 kg/m2)). Results: Among the responders, 43% were overweight and 42% were obese. The hazard ratio for normal versus overweight was 0.81 (95% Confidence Interval (CI), 0.75–0.88); normal versus obese 0.71 (95%CI, 0.66, 0.77); and overweight versus obese 0.88 (95%CI, 0.83–0.92). Conclusion: GERD diagnoses rates were higher in overweight and obese WTC responders. Am. J. Ind. Med. 59:761–766, 2016.

KW - 9/11

KW - BMI

KW - GERD

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U2 - 10.1002/ajim.22637

DO - 10.1002/ajim.22637

M3 - Article

C2 - 27582478

AN - SCOPUS:84984797236

SN - 0271-3586

VL - 59

SP - 761

EP - 766

JO - American Journal of Industrial Medicine

JF - American Journal of Industrial Medicine

IS - 9

ER -

The association between body mass index and gastroesophageal reflux disease in the World Trade Center Health Program General Responder Cohort

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Keywords

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