@inbook{f10d58f6d8e044e592bbfe5ab7f356ad,
title = "The Architecture of a Precision Oncology Platform",
abstract = "Precision oncology is a novel research field and approach to cancer care which leverages high-throughput sequencing technologies and bioinformatics pipelines to determine diagnosis, prognosis, and treatment of patients in a personalized manner. This chapter provides an overview of a typical precision oncology software platform, from raw data to patient reports. Standard and advanced analytical components are described and discussed, along with their strengths and limitations, in general and in the context of a precision oncology application for advanced cancer patients.",
keywords = "Actionable alterations, Biomarkers, Drug recommendations, High-throughput next-generation sequencing, Mutations, Patient reports, Precision oncology, RNA sequencing, Whole-exome sequencing, Whole-genome sequencing",
author = "Alessandro Lagan{\`a}",
note = "Publisher Copyright: {\textcopyright} 2022, Springer Nature Switzerland AG.",
year = "2022",
doi = "10.1007/978-3-030-91836-1_1",
language = "English",
series = "Advances in Experimental Medicine and Biology",
publisher = "Springer",
pages = "1--22",
booktitle = "Advances in Experimental Medicine and Biology",
address = "Germany",
}