TY - JOUR
T1 - The application of deep brain stimulation in the treatment of psychiatric disorders
AU - Graat, Ilse
AU - Figee, Martijn
AU - Denys, Damiaan
N1 - Publisher Copyright:
© 2017 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.
PY - 2017/3/4
Y1 - 2017/3/4
N2 - Deep brain stimulation (DBS) is a last-resort treatment for neurological and psychiatric disorders that are refractory to standard treatment. Over the last decades, the progress of DBS in psychiatry has been slower than in neurology, in part owing to the heterogenic symptomatology and complex neuroanatomy of psychiatric disorders. However, for obsessive-compulsive disorder (OCD) DBS is now an accepted treatment. This study first reviews clinical outcomes and mechanisms of DBS for OCD, and then discusses these results in an overview of current and future psychiatric applications, including DBS for mood disorders, Tourette’s syndrome, addiction, anorexia nervosa, autism, schizophrenia, and anxiety disorders. In addition, it will focus on novel techniques that may enhance the application of DBS in psychiatry.
AB - Deep brain stimulation (DBS) is a last-resort treatment for neurological and psychiatric disorders that are refractory to standard treatment. Over the last decades, the progress of DBS in psychiatry has been slower than in neurology, in part owing to the heterogenic symptomatology and complex neuroanatomy of psychiatric disorders. However, for obsessive-compulsive disorder (OCD) DBS is now an accepted treatment. This study first reviews clinical outcomes and mechanisms of DBS for OCD, and then discusses these results in an overview of current and future psychiatric applications, including DBS for mood disorders, Tourette’s syndrome, addiction, anorexia nervosa, autism, schizophrenia, and anxiety disorders. In addition, it will focus on novel techniques that may enhance the application of DBS in psychiatry.
KW - DBS
KW - Deep brain stimulation
KW - applications
KW - psychiatry
UR - http://www.scopus.com/inward/record.url?scp=85019564962&partnerID=8YFLogxK
U2 - 10.1080/09540261.2017.1282439
DO - 10.1080/09540261.2017.1282439
M3 - Review article
C2 - 28523977
AN - SCOPUS:85019564962
SN - 0954-0261
VL - 29
SP - 178
EP - 190
JO - International Review of Psychiatry
JF - International Review of Psychiatry
IS - 2
ER -