Thallium 201 for myocardial imaging. Relation of thallium 201 to regional myocardial perfusion

H. W. Strauss, K. Harrison, J. K. Langan, E. Lebowitz, B. Pitt

Research output: Contribution to journalArticlepeer-review

398 Scopus citations

Abstract

Following i.v. administration, the myocardial concentration of tracer thallium 201, potassium 43, and rubidium 81 were determined in mice; thallium was present in the greatest concentration in the myocardium (2.08% compared 1.25% for potassium and 1.15% for rubidium at 10 min). The regional myocardial distribution of thallium 201 was determined in dogs under conditions of normal flow, and total occlusion, and compared with potassium 43 (r = 0.97). The regional distribution of thallium 201 was compared to microspheres under conditions of partial occlusion and reactive hyperemia (r = 0.97). Thallium 201 was evaluated in a series of phantom scans, which demonstrated that the low energy X ray of thallium was suitable for imaging. These results suggest that thallium 201 can be used for the evaluation of the distribution of regional myocardial perfusion.

Original languageEnglish
Pages (from-to)641-645
Number of pages5
JournalUnknown Journal
Volume51
Issue number4
DOIs
StatePublished - 1975
Externally publishedYes

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