Textures of the tumour microenvironment

Julie S. Di Martino, Chandrani Mondal, Jose Javier Bravo-Cordero

Research output: Contribution to journalReview articlepeer-review

10 Scopus citations


In this review, we present recent findings on the dynamic nature of the tumour microenvironment (TME) and how intravital microscopy studies have defined TME components in a spatiotemporal manner. Intravital microscopy has shed light into the nature of the TME, revealing structural details of both tumour cells and other TME co-habitants in vivo, how these cells communicate with each other, and how they are organized in three-dimensional space to orchestrate tumour growth, invasion, dissemination and metastasis. We will review different imaging tools, imaging reporters and fate-mapping strategies that have begun to uncover the complexity of the TME in vivo.

Original languageEnglish
Pages (from-to)619-629
Number of pages11
JournalEssays in Biochemistry
Issue number5
StatePublished - 2019


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