Testing long-term memory in animal models of schizophrenia: Suggestions from CNTRICS

Timothy J. Bussey, Deanna M. Barch, Mark G. Baxter

Research output: Contribution to journalReview articlepeer-review

21 Scopus citations

Abstract

This paper reports the results of discussions at the fourth meeting of Cognitive Neuroscience Treatment Research to Improve Cognition in Schizophrenia (CNTRICS) meeting, held over two days in Washington, DC in April 2011. The meeting focused on animal paradigms for assessing the cognitive constructs relevant to schizophrenia identified in previous CNTRICS meetings. This report focuses on the outcome of discussions in the general area of long-term memory. A number of candidate animal paradigms were discussed. Two of these - one for rodents and one for non-human primates - were recommended as particularly promising for further development.

Original languageEnglish
Pages (from-to)2141-2148
Number of pages8
JournalNeuroscience and Biobehavioral Reviews
Volume37
Issue number9
DOIs
StatePublished - Nov 2013

Keywords

  • Episodic memory
  • Hippocampus
  • Mouse
  • Neuropsychiatric disease
  • Object recognition
  • Paired-associate learning
  • Prefrontal cortex
  • Rat
  • Relational memory
  • Rodent
  • Touchscreen

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