Temporal frequency-dependent vep changes in Parkinson's disease

Marcy Marx; Ivan Bodis-Wollner; Phyllis Bobak; Carmen Harnois; Lee Mylin; Melvin Yahr

doi:10.1016/0042-6989(86)90080-5

Temporal frequency-dependent vep changes in Parkinson's disease

Marcy Marx, Ivan Bodis-Wollner, Phyllis Bobak, Carmen Harnois, Lee Mylin, Melvin Yahr

Icahn School of Medicine at Mount Sinai

Research output: Contribution to journal › Article › peer-review

54 Scopus citations

Abstract

We recorded steady-state (4.19 and 8.41 Hz) VEPs in 17 Parkinson's Disease (PD) patients and 18 control observers using on off temporal modulation of a 2.3 c/deg sinusoidal grating. With 4.19 Hz. 20 out of 33 PD patient eyes had abnormal VEPs. However, only 8 of 33 eyes were abnormal with 8.41 Hz. "Routine" (counterphase) transient VEPs revealed delayed VEPs for only 7 out of 24 eyes of the patients. These findings suggest an "input" temporal frequency-dependent abnormality in the foveal pathway.

Original language	English
Pages (from-to)	185-193
Number of pages	9
Journal	Vision Research
Volume	26
Issue number	1
DOIs	https://doi.org/10.1016/0042-6989(86)90080-5
State	Published - 1986

Keywords

Disease
Nonlinear processing
On-off modulation
Parkinson's
Sequential processing
Temporal frequency
VEP

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keywords = "Disease, Nonlinear processing, On-off modulation, Parkinson's, Sequential processing, Temporal frequency, VEP",

author = "Marcy Marx and Ivan Bodis-Wollner and Phyllis Bobak and Carmen Harnois and Lee Mylin and Melvin Yahr",

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T1 - Temporal frequency-dependent vep changes in Parkinson's disease

AU - Marx, Marcy

AU - Bodis-Wollner, Ivan

AU - Bobak, Phyllis

AU - Harnois, Carmen

AU - Mylin, Lee

AU - Yahr, Melvin

PY - 1986

Y1 - 1986

N2 - We recorded steady-state (4.19 and 8.41 Hz) VEPs in 17 Parkinson's Disease (PD) patients and 18 control observers using on off temporal modulation of a 2.3 c/deg sinusoidal grating. With 4.19 Hz. 20 out of 33 PD patient eyes had abnormal VEPs. However, only 8 of 33 eyes were abnormal with 8.41 Hz. "Routine" (counterphase) transient VEPs revealed delayed VEPs for only 7 out of 24 eyes of the patients. These findings suggest an "input" temporal frequency-dependent abnormality in the foveal pathway.

AB - We recorded steady-state (4.19 and 8.41 Hz) VEPs in 17 Parkinson's Disease (PD) patients and 18 control observers using on off temporal modulation of a 2.3 c/deg sinusoidal grating. With 4.19 Hz. 20 out of 33 PD patient eyes had abnormal VEPs. However, only 8 of 33 eyes were abnormal with 8.41 Hz. "Routine" (counterphase) transient VEPs revealed delayed VEPs for only 7 out of 24 eyes of the patients. These findings suggest an "input" temporal frequency-dependent abnormality in the foveal pathway.

KW - Disease

KW - Nonlinear processing

KW - On-off modulation

KW - Parkinson's

KW - Sequential processing

KW - Temporal frequency

KW - VEP

UR - https://www.scopus.com/pages/publications/0022650660

U2 - 10.1016/0042-6989(86)90080-5

DO - 10.1016/0042-6989(86)90080-5

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AN - SCOPUS:0022650660

SN - 0042-6989

VL - 26

SP - 185

EP - 193

JO - Vision Research

JF - Vision Research

IS - 1

ER -

Temporal frequency-dependent vep changes in Parkinson's disease

Abstract

Keywords

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