TY - JOUR
T1 - Temperamental correlates of disruptive behavior disorders in young children
T2 - Preliminary findings
AU - Hirshfeld-Becker, Dina R.
AU - Biederman, Joseph
AU - Faraone, Stephen V.
AU - Violette, Heather
AU - Wrightsman, Jessica
AU - Rosenbaum, Jerrold F.
N1 - Funding Information:
National Institute of Mental Health Grant Nos. MH-47077-05 (Drs. Rosenbaum and Biederman) and MH-01538-02 (Dr. Hirshfeld-Becker) supported this research. The authors gratefully acknowledge Dr. Jerome Kagan and Dr. Nancy Snidman at the Department of Psychology at Harvard University for their contributions to this project. We acknowledge Dr. David Rettew for his contribution to reliability assessments.
PY - 2002/4/1
Y1 - 2002/4/1
N2 - Background: Our objective was to test the hypothesis that temperamental behavioral disinhibition measured in early childhood would be associated with disruptive behavior disorders. Methods: We used variables from laboratory-based behavioral observations originally devised to assess behavioral inhibition to construct a theory-based a priori definition of "behavioral disinhibition" in 200 young children at-risk for panic disorder, depression, or both and 84 children of parents without anxiety or major depressive disorder. We then compared behaviorally disinhibited and nonbehaviorally disinhibited children on rates of DSM-III-R disorders and measures of academic and social dysfunction. Results: Behavioral disinhibition was significantly associated with higher rates of disruptive behavior disorders and mood disorders. Children with behavioral disinhibition were significantly more likely than nondisinhibited, noninhibited children to have attention-deficit/hyperactivity disorder (ADHD) and to have comorbid mood and disruptive behavior disorders. Moreover, disinhibited children had lower Global Assessment of Functioning Scale scores and were more likely to have been in special classes and to have problems with school behavior and leisure activities. Conclusions: These results suggest that behavioral disinhibition may represent a temperamental precursor to disruptive behavior problems, particularly ADHD. Longitudinal studies using behavioral assessments of behavioral disinhibition are needed to confirm these findings.
AB - Background: Our objective was to test the hypothesis that temperamental behavioral disinhibition measured in early childhood would be associated with disruptive behavior disorders. Methods: We used variables from laboratory-based behavioral observations originally devised to assess behavioral inhibition to construct a theory-based a priori definition of "behavioral disinhibition" in 200 young children at-risk for panic disorder, depression, or both and 84 children of parents without anxiety or major depressive disorder. We then compared behaviorally disinhibited and nonbehaviorally disinhibited children on rates of DSM-III-R disorders and measures of academic and social dysfunction. Results: Behavioral disinhibition was significantly associated with higher rates of disruptive behavior disorders and mood disorders. Children with behavioral disinhibition were significantly more likely than nondisinhibited, noninhibited children to have attention-deficit/hyperactivity disorder (ADHD) and to have comorbid mood and disruptive behavior disorders. Moreover, disinhibited children had lower Global Assessment of Functioning Scale scores and were more likely to have been in special classes and to have problems with school behavior and leisure activities. Conclusions: These results suggest that behavioral disinhibition may represent a temperamental precursor to disruptive behavior problems, particularly ADHD. Longitudinal studies using behavioral assessments of behavioral disinhibition are needed to confirm these findings.
KW - Attention-deficit/hyperactivity disorder
KW - Behavioral disinhibition
KW - Disruptive behavior disorders
KW - Mood disorders
KW - Psychopathology
UR - http://www.scopus.com/inward/record.url?scp=0036537078&partnerID=8YFLogxK
U2 - 10.1016/S0006-3223(01)01299-9
DO - 10.1016/S0006-3223(01)01299-9
M3 - Article
C2 - 11950458
AN - SCOPUS:0036537078
SN - 0006-3223
VL - 51
SP - 563
EP - 574
JO - Biological Psychiatry
JF - Biological Psychiatry
IS - 7
ER -