Telangiectatic oncocytoma: A previously undescribed variant of renal oncocytoma

Guang Qian Xiao, Huai Bin Mabel Ko, Pamela Unger

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

Objectives: To identify, describe, and investigate the clinical, radiologic, and pathologic features of 8 cases of telangiectatic oncocytoma. Methods: Fifty-three consecutive renal oncocytomas were reviewed for the telangiectatic pathologic features that were subsequently correlated with the demographic, clinical, and radiographic findings. Results: Telangiectatic oncocytoma accounted for 15% of the 53 renal oncocytomas collected in the past 7 years in our institution. On radiology, almost all presented as an enhancing mass and were suspicious for or consistent with a renal malignant tumor. Grossly, the tumors ranged from 2.4 to 6.0 cm (mean, 3.5 cm) and macroscopically were hemorrhagic spongy or multicystic masses without a central stellate scar. Microscopically, they were characterized by variably sized blood-distended spaces (<0.1-mm to 2- to 3-mm blood lakes) lined by typical oncocytoma cells and without evidence of degenerative changes. Conclusions: With its unique radiologic and pathologic presentations in comparison with classic renal oncocytoma, it is important to recognize this new variant of renal oncocytoma.

Original languageEnglish
Pages (from-to)103-108
Number of pages6
JournalAmerican Journal of Clinical Pathology
Volume140
Issue number1
DOIs
StatePublished - Jul 2013

Keywords

  • Cystic
  • Oncocytoma
  • Renal
  • Telangiectatic

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