Technology Insight: Magnetic resonance angiography for the evaluation of patients with peripheral artery disease

  • Santo Dellegrottaglie
  • , Javier Sanz
  • , Frank Macaluso
  • , Andrew J. Einstein
  • , Subha Raman
  • , Orlando P. Simonetti
  • , Sanjay Rajagopalan

Research output: Contribution to journalReview articlepeer-review

23 Scopus citations

Abstract

Peripheral arterial disease (PAD) is a common manifestation of systemic atherosclerosis. Although clinical history in conjunction with ankle-brachial index and evaluation of segmental pressures/waveforms is sufficient to diagnose PAD in a large percentage of patients, imaging is required for disease localization and treatment planning. Contrast-enhanced magnetic resonance angiography (CE-MRA) is a noninvasive, three-dimensional technique that has emerged as a front-line imaging approach for comprehensive evaluation of PAD. Technical advances such as parallel imaging and moving-table, time-resolved angiography and extended field-of-view approaches have greatly improved the accuracy of CE-MRA. In the clinical setting, CE-MRA can be extremely helpful in the initial diagnosis as well as subsequent management of patients with PAD. Continued hardware and software improvements will enable further refinements in imaging protocol for peripheral MRA, consolidating its clinical role for the evaluation of patients with PAD.

Original languageEnglish
Pages (from-to)677-687
Number of pages11
JournalNature Clinical Practice Cardiovascular Medicine
Volume4
Issue number12
DOIs
StatePublished - Dec 2007

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