Taking it up a notch in MCL

Research output: Contribution to journalComment/debate

1 Scopus citations


In this issue of Blood, Kridel et al describe recurrent NOTCH1 mutations in mantle cell lymphoma (MCL) by next-generation sequencing of patient samples and cell lines. They further demonstrate a negative prognostic impact of NOTCH1 mutation in their cohort of patients and sensitivity of MCL cells to NOTCH1 inhibition in vitro, suggesting a novel role for NOTCH1 in this disease.

Original languageEnglish
Pages (from-to)1957-1958
Number of pages2
Issue number9
StatePublished - 1 Mar 2012
Externally publishedYes


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