Systemic agents for the treatment of atopic dermatitis

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


Atopic dermatitis (AD) is a chronic inflammatory skin condition with the potential for great social, economic, and psychological morbidity (Hong et al. 2008). A variety of treatment modalities are available for the management of AD, ranging from topical emollients to powerful systemic immunosuppressive agents with potentially serious side effects. Topical therapies include corticosteroid preparations, topical antibiotics, calcineurin inhibitors, and wet wraps followed by emollients or topical corticosteroids. In more severe cases refractory to topical treatment, phototherapy, systemic antibiotics, sedating antihistamines, leukotriene antagonists, systemic corticosteroids, and other immunomodulators may be of value. This chapter reviews the use of systemic immunomodulatory agents for the treatment of AD.

Original languageEnglish
Title of host publicationAtopic Dermatitis and Eczematous Disorders
PublisherCRC Press
Number of pages13
ISBN (Electronic)9781840766530
ISBN (Print)9781840761955
StatePublished - 1 Jan 2014


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