Syphilitic Gastritis in an HIV‐infected Individual

Franklin Kasmin, Satish Reddy, Usha Mathur‐Wagh, Jonathan Sariin, Alice Goldman, Howard Antosofsky, Natalie Strutynsky

Research output: Contribution to journalArticlepeer-review

17 Scopus citations

Abstract

We report the first known case of syphilitic gastritis in an HIV‐infected person. The presentation of nonspecific abdominal pain and weight loss in a 48‐yr‐old former intravenous drug user previously treated for asymptomatic syphilis led to a barium swallow which demonstrated linitis plastica. Upper endoscopy reinforced a suspicion of carcinoma, but biopsy made the diagnosis of syphilis by silver staining. Further testing revealed a positive serology for syphilis as well as HIV infection with a depressed CD‐4 lymphocyte count. Treatment with parenteral penicillin led to a rapid resolution of symptoms. This case represents a rare complication of late syphilis, and is another example of the unusual manifestations of syphilis seen in the HIV‐infected population.

Original languageEnglish
Pages (from-to)1820-1822
Number of pages3
JournalAmerican Journal of Gastroenterology
Volume87
Issue number12
DOIs
StatePublished - Dec 1992

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