TY - JOUR
T1 - Synthesis, spectral characterization and biological activity of zinc(II) complexes with 3-substituted phenyl-4-amino-5-hydrazino-1, 2, 4-triazole Schiff bases
AU - Singh, A. K.
AU - Pandey, O. P.
AU - Sengupta, S. K.
N1 - Funding Information:
The authors are thankful to the Head, Sophisticated Analytical Instrument Facility, Central Drug Research Institute, Lucknow , for providing IR, 1 H NMR, 13 C NMR and FAB mass spectra data. We thank the UGC [Ref.F.4-5/2006 (XI plan)/23 dated Jan 12, 2007) for financial support. Authors are also thankful to Department of Biotechnology, D.D.U. Gorakhpur University, Gorakhpur , for help in evaluating antibacterial activities.
PY - 2012/1
Y1 - 2012/1
N2 - New Zn(II) complexes have been synthesized by the reactions of zinc(II) acetate with Schiff bases derived from 3-substituted phenyl-4-amino-5-hydrazino- 1, 2, 4-triazole and benzaldehyde, 2-hydroxyacetophenone or indoline-2,3-dione. All these complexes are soluble in DMF and DMSO; low molar conductance values indicate that they are non-electrolytes. Elemental analyses suggest that the complexes have 1:1 stoichiometry of the type [ZnL(H 2O) 2], [ZnL′(OAc) 2(H 2O) 2] (L = dianionic Schiff bases derived from 3-(substituted phenyl)-4-amino-5-hydrazino-1, 2, 4-triazole and 2-hydroxyacetophenone or indoline-2,3-dione; L′ = neutral Schiff bases derived from 3-(substituted phenyl)-4-amino-5-hydrazino-1, 2, 4-triazole and benzaldehyde) and they were characterized by FT-IR, 1H NMR, 13C NMR and FAB mass. All these Schiff bases and their complexes have also been screened for their antibacterial activities against Bacillus subtilis, Escherichia coli and antifungal activities against Colletotrichum falcatum, Aspergillus niger, Fusarium oxysporium and Carvularia pallescence by petriplates methods.
AB - New Zn(II) complexes have been synthesized by the reactions of zinc(II) acetate with Schiff bases derived from 3-substituted phenyl-4-amino-5-hydrazino- 1, 2, 4-triazole and benzaldehyde, 2-hydroxyacetophenone or indoline-2,3-dione. All these complexes are soluble in DMF and DMSO; low molar conductance values indicate that they are non-electrolytes. Elemental analyses suggest that the complexes have 1:1 stoichiometry of the type [ZnL(H 2O) 2], [ZnL′(OAc) 2(H 2O) 2] (L = dianionic Schiff bases derived from 3-(substituted phenyl)-4-amino-5-hydrazino-1, 2, 4-triazole and 2-hydroxyacetophenone or indoline-2,3-dione; L′ = neutral Schiff bases derived from 3-(substituted phenyl)-4-amino-5-hydrazino-1, 2, 4-triazole and benzaldehyde) and they were characterized by FT-IR, 1H NMR, 13C NMR and FAB mass. All these Schiff bases and their complexes have also been screened for their antibacterial activities against Bacillus subtilis, Escherichia coli and antifungal activities against Colletotrichum falcatum, Aspergillus niger, Fusarium oxysporium and Carvularia pallescence by petriplates methods.
KW - Antifungal and antibacterial
KW - C NMR
KW - FT-IR
KW - H NMR
KW - Schiff bases
KW - Zn(II)
UR - http://www.scopus.com/inward/record.url?scp=81155151276&partnerID=8YFLogxK
U2 - 10.1016/j.saa.2011.08.019
DO - 10.1016/j.saa.2011.08.019
M3 - Article
C2 - 22029966
AN - SCOPUS:81155151276
SN - 1386-1425
VL - 85
SP - 1
EP - 6
JO - Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy
JF - Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy
IS - 1
ER -