Synthesis, reactivity, and NMR spectroscopy of 4,6- and 6,7-difluoro-3-methyl-1H-indazoles

Carlos Pérez Medina; Concepción López; Rosa M. Claramunt; José Elguero

doi:10.1002/jhet.202

Synthesis, reactivity, and NMR spectroscopy of 4,6- and 6,7-difluoro-3-methyl-1H-indazoles

Carlos Pérez Medina, Concepción López, Rosa M. Claramunt, José Elguero

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

(Chemical Equation Presented) Four 1H-indazoles, two of them doubly substituted by fluorine atoms and the other two obtained by nitration of the foregoing derivatives, were prepared and fully characterized by multinuclear NMR in solution and in solid state in view of their potential nitric oxide synthase inhibition properties.

Original language	English
Pages (from-to)	1408-1412
Number of pages	5
Journal	Journal of Heterocyclic Chemistry
Volume	46
Issue number	6
DOIs	https://doi.org/10.1002/jhet.202
State	Published - Nov 2009
Externally published	Yes

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title = "Synthesis, reactivity, and NMR spectroscopy of 4,6- and 6,7-difluoro-3-methyl-1H-indazoles",

abstract = "(Chemical Equation Presented) Four 1H-indazoles, two of them doubly substituted by fluorine atoms and the other two obtained by nitration of the foregoing derivatives, were prepared and fully characterized by multinuclear NMR in solution and in solid state in view of their potential nitric oxide synthase inhibition properties.",

author = "Medina, {Carlos P{\'e}rez} and Concepci{\'o}n L{\'o}pez and Claramunt, {Rosa M.} and Jos{\'e} Elguero",

year = "2009",

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doi = "10.1002/jhet.202",

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T1 - Synthesis, reactivity, and NMR spectroscopy of 4,6- and 6,7-difluoro-3-methyl-1H-indazoles

AU - Medina, Carlos Pérez

AU - López, Concepción

AU - Claramunt, Rosa M.

AU - Elguero, José

PY - 2009/11

Y1 - 2009/11

N2 - (Chemical Equation Presented) Four 1H-indazoles, two of them doubly substituted by fluorine atoms and the other two obtained by nitration of the foregoing derivatives, were prepared and fully characterized by multinuclear NMR in solution and in solid state in view of their potential nitric oxide synthase inhibition properties.

AB - (Chemical Equation Presented) Four 1H-indazoles, two of them doubly substituted by fluorine atoms and the other two obtained by nitration of the foregoing derivatives, were prepared and fully characterized by multinuclear NMR in solution and in solid state in view of their potential nitric oxide synthase inhibition properties.

UR - http://www.scopus.com/inward/record.url?scp=72249084133&partnerID=8YFLogxK

U2 - 10.1002/jhet.202

DO - 10.1002/jhet.202

M3 - Article

AN - SCOPUS:72249084133

SN - 0022-152X

VL - 46

SP - 1408

EP - 1412

JO - Journal of Heterocyclic Chemistry

JF - Journal of Heterocyclic Chemistry

IS - 6

ER -

Synthesis, reactivity, and NMR spectroscopy of 4,6- and 6,7-difluoro-3-methyl-1H-indazoles

Abstract

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