Synthesis, Pim kinase inhibitory potencies and in vitro antiproliferative activities of diversely substituted pyrrolo[2,3-a]carbazoles

Keyphrases

• Inhibitory Potency 100%
• Pyrrol 100%
• PIM Kinase 100%
• Carbazole 100%
• In Vitro Antiproliferative Activity 100%
• Human Fibroblasts 50%
• Cancer Cell Lines 50%
• DU145 50%
• Primary Culture 50%
• Inhibitory Activity 50%
• Solid Cancer 50%
• Active Compounds 50%
• PIM-1 50%
• PIM2 50%
• Molecular Docking Studies 50%
• PA-1 50%
• PIM3 50%
• Carbazole Derivatives 50%

Pharmacology, Toxicology and Pharmaceutical Science

• Phosphotransferase 100%
• Antiproliferative Activity 100%
• Carbazole Derivative 100%
• Malignant Neoplasm 50%
• Primary Culture 50%
• Protein Kinase Pim 1 50%