Synthesis of sulfosucrose derivatives for evaluation as regulators of fibroblast growth factor activity

Tülay Polat, Moosa Mohammadi, Robert J. Linhardt

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

Based on X-ray crystallographic studies on sucrose octasulfate in complex with fibroblast growth factor and its receptor, three analogs of sucrose octasulfate were regioselectively synthesized for biological evaluation as regulations of cell proliferation and differentiation.

Original languageEnglish
Pages (from-to)8047-8049
Number of pages3
JournalTetrahedron Letters
Volume43
Issue number45
DOIs
StatePublished - 4 Nov 2002
Externally publishedYes

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