Synthesis of hydrogen-bond surrogate α-helices as inhibitors of protein-protein interactions

Keyphrases

• Proteinase Inhibitor 100%
• Hydrogen Bond Surrogate 100%
• Helix 100%
• Protein-protein Interaction 60%
• Hydrogen Bonds (H-bonds) 20%
• Dysregulated 20%
• Secondary Amines 20%
• I to 20%
• Disease States 20%
• Covalent Bond 20%
• Secondary Structure 20%
• Allyl 20%
• Peptidomimetics 20%
• Cellular Uptake 20%
• Solid-phase Synthesis 20%
• Solid-phase Peptide Synthesis 20%
• Conformational Stability 20%
• Ring-closing Metathesis 20%
• Peptide Coupling 20%
• Linear Peptide 20%

Biochemistry, Genetics and Molecular Biology

• Protein-Protein Interaction 100%
• Hydrogen Bond 100%
• N-Terminus 20%
• Protein Secondary Structure 20%
• Covalent Bond 20%
• Solid 20%
• Peptide Synthesis 20%
• Peptide Mimetics 20%
• Ring Closing Metathesis 20%
• Solid Phase Synthesis 20%

Chemistry

• Protein Interaction 100%
• Hydrogen Bond 100%
• Secondary Structure 20%
• Peptide Synthesis 20%
• Ring Closing Metathesis 20%
• Covalent Bond 20%
• Secondary Amine 20%
• Peptide Coupling 20%
• stability 20%