Synthesis of highly functionalized pyrrolidines via a mild one-pot, three-component 1,3-dipolar cycloaddition process

Keyphrases

• Pyrrolidine 100%
• 1,3-dipolar Cycloaddition 100%
• One-pot Three-component 100%
• Azomethine Ylide 66%
• Mild Reaction Conditions 33%
• Regioselectivity 33%
• Aldehydes 33%
• Dimethyl 33%
• Ag(I) 33%
• Methyl Acrylate 33%
• Electron-deficient Alkenes 33%
• Regio 33%
• Stereoselectivity 33%
• Excellent Yields 33%
• Maleic Anhydride 33%
• Imines 33%
• Aminomalonates 33%
• One-pot Three-component Synthesis 33%
• Dipolarophile 33%
• N-phenylmaleimide 33%
• Cleaner Production 33%
• Enolizable Aldehydes 33%

Chemistry

• Pyrrolidine 100%
• 1,3-cycloaddition 100%
• Azomethine Ylide 66%
• Regioselectivity 33%
• Alkene 33%
• Methyl Acrylate 33%
• Stereoselectivity 33%
• Maleimide 33%
• Imine 33%
• Maleic Anhydride 33%