TY - GEN
T1 - Synthesis of biocompatible magnetic iron oxide (γ-Fe 2O3 and Fe3O4) nanoparticles by a modified polyol process for biomedical applications
AU - Basina, Georgia
AU - Panagiotopoulos, Ioannis
AU - Devlin, Eamonn
AU - Hadjipanayis, George
AU - Colak, Levent
AU - Hadjipanayis, Costas
AU - Mao, Hui
AU - Diamantopoulos, Georgios
AU - Fardis, Michael
AU - Papavassiliou, Georgios
AU - Niarchos, Dimitris
AU - Tzitzios, Vasilis
PY - 2010
Y1 - 2010
N2 - Highly crystalline superparamagnetic Fe3O4 nanoparticles coated by polyvinylpyrrolidone (PVP) were prepared by simultaneous thermal decomposition of ferrous and ferric inorganic salts in polyethylene glycol (PEG) with molecular weight 200. The magnetic particles have a diameter in the range of 8-15 nm, and after exchange with citric acid diammonium salt, they transform into very stable super hydrophilic colloidal solutions. The presence of magnetite phase was confirmed using powder X-rays diffraction (XRD) and Mössbauer spectroscopy, while thermogravimetric analysis and FT-IR spectroscopy confirmed the presence of PVP or citrate anions on the nanoparticles surface. The magnetic properties revealed superparamagnetic behavior, with the composite material showing a saturation magnetization up to 57 emu/g. The Fe3O4 nanoparticles prepared by this modified polyol process are suitable for biomedical applications because of the biocompatibility of citrate anions. Magnetic hyperthermia experiments in neutral water solutions shows that the particles induce fast heating rates with specific absorption rate (SAR) values which reached 57.53 W/gFe, when the concentration of iron is 11.2 mgFe/ml.
AB - Highly crystalline superparamagnetic Fe3O4 nanoparticles coated by polyvinylpyrrolidone (PVP) were prepared by simultaneous thermal decomposition of ferrous and ferric inorganic salts in polyethylene glycol (PEG) with molecular weight 200. The magnetic particles have a diameter in the range of 8-15 nm, and after exchange with citric acid diammonium salt, they transform into very stable super hydrophilic colloidal solutions. The presence of magnetite phase was confirmed using powder X-rays diffraction (XRD) and Mössbauer spectroscopy, while thermogravimetric analysis and FT-IR spectroscopy confirmed the presence of PVP or citrate anions on the nanoparticles surface. The magnetic properties revealed superparamagnetic behavior, with the composite material showing a saturation magnetization up to 57 emu/g. The Fe3O4 nanoparticles prepared by this modified polyol process are suitable for biomedical applications because of the biocompatibility of citrate anions. Magnetic hyperthermia experiments in neutral water solutions shows that the particles induce fast heating rates with specific absorption rate (SAR) values which reached 57.53 W/gFe, when the concentration of iron is 11.2 mgFe/ml.
UR - http://www.scopus.com/inward/record.url?scp=79951970631&partnerID=8YFLogxK
U2 - 10.1557/proc-1256-n06-35
DO - 10.1557/proc-1256-n06-35
M3 - Conference contribution
AN - SCOPUS:79951970631
SN - 9781617822209
T3 - Materials Research Society Symposium Proceedings
SP - 174
EP - 180
BT - Functional Oxide Nanostructures and Heterostructures
PB - Materials Research Society
ER -