Synthesis of 2′,3′-Di-O-acetylfrangulin A and prinoidin, two novel anthracene L-rhamnopyranosides isolated from Rhamnus nepalensis

Gao Peng Song; Peng Wang; Zai Hong Zhang; Da Kuo Shi; Ying Xia Li

doi:10.1002/cjoc.200890310

Synthesis of 2′,3′-Di-O-acetylfrangulin A and prinoidin, two novel anthracene L-rhamnopyranosides isolated from Rhamnus nepalensis

Gao Peng Song, Peng Wang, Zai Hong Zhang, Da Kuo Shi, Ying Xia Li

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

The total synthesis of 2′,3′-di-O-acetylfrangulin A (1) and prinoidin (2), which were isolated from Rhamnus nepalensis and showed significant cytotoxicity to KB cell line, was achieved for the first time. The structures of the two compounds were confirmed by ¹H NMR, ¹³C NMR, ¹H-¹H COSY, HMQC and HMBC.

Original language	English
Pages (from-to)	1715-1720
Number of pages	6
Journal	Chinese Journal of Chemistry
Volume	26
Issue number	9
DOIs	https://doi.org/10.1002/cjoc.200890310
State	Published - Sep 2008
Externally published	Yes

Keywords

2′,3′-di-O-acetylfrangulin A
Prinoidin
Rhamnosylanthrone
Synthesis

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10.1002/cjoc.200890310

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title = "Synthesis of 2′,3′-Di-O-acetylfrangulin A and prinoidin, two novel anthracene L-rhamnopyranosides isolated from Rhamnus nepalensis",

abstract = "The total synthesis of 2′,3′-di-O-acetylfrangulin A (1) and prinoidin (2), which were isolated from Rhamnus nepalensis and showed significant cytotoxicity to KB cell line, was achieved for the first time. The structures of the two compounds were confirmed by 1H NMR, 13C NMR, 1H-1H COSY, HMQC and HMBC.",

keywords = "2′,3′-di-O-acetylfrangulin A, Prinoidin, Rhamnosylanthrone, Synthesis",

author = "Song, {Gao Peng} and Peng Wang and Zhang, {Zai Hong} and Shi, {Da Kuo} and Li, {Ying Xia}",

year = "2008",

month = sep,

doi = "10.1002/cjoc.200890310",

language = "English",

volume = "26",

pages = "1715--1720",

journal = "Chinese Journal of Chemistry",

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AU - Song, Gao Peng

AU - Wang, Peng

AU - Zhang, Zai Hong

AU - Shi, Da Kuo

AU - Li, Ying Xia

PY - 2008/9

Y1 - 2008/9

N2 - The total synthesis of 2′,3′-di-O-acetylfrangulin A (1) and prinoidin (2), which were isolated from Rhamnus nepalensis and showed significant cytotoxicity to KB cell line, was achieved for the first time. The structures of the two compounds were confirmed by 1H NMR, 13C NMR, 1H-1H COSY, HMQC and HMBC.

AB - The total synthesis of 2′,3′-di-O-acetylfrangulin A (1) and prinoidin (2), which were isolated from Rhamnus nepalensis and showed significant cytotoxicity to KB cell line, was achieved for the first time. The structures of the two compounds were confirmed by 1H NMR, 13C NMR, 1H-1H COSY, HMQC and HMBC.

KW - 2′,3′-di-O-acetylfrangulin A

KW - Prinoidin

KW - Rhamnosylanthrone

KW - Synthesis

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U2 - 10.1002/cjoc.200890310

DO - 10.1002/cjoc.200890310

M3 - Article

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VL - 26

SP - 1715

EP - 1720

JO - Chinese Journal of Chemistry

JF - Chinese Journal of Chemistry

IS - 9

ER -

Synthesis of 2′,3′-Di-O-acetylfrangulin A and prinoidin, two novel anthracene L-rhamnopyranosides isolated from Rhamnus nepalensis

Abstract

Keywords

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