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Synthesis and SAR studies of dual AKT/NF-κB inhibitors against melanoma
Elisa Barile
, Surya K. De
, Yongmei Feng
, Vida Chen
, Li Yang
,
Ze'ev Ronai
, Maurizio Pellecchia
Research output
:
Contribution to journal
›
Article
›
peer-review
20
Scopus citations
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Keyphrases
Melanoma
100%
NF-B
100%
Synthesis Study
100%
SAR Study
100%
RB Pathway
75%
Xenograft Model
50%
Prostate Cell Line
50%
Melanoma Cells
50%
Breast Cell Lines
50%
Melanoma Xenografts
50%
AKT1
25%
Tumor Progression
25%
Phosphorylation
25%
Nuclear factor-κB
25%
Tumor Subtype
25%
Tumor Development
25%
Signaling Events
25%
Central Regulator
25%
Protein Kinase B
25%
Cellular Signaling
25%
Fluorinated Derivatives
25%
BI-69A11
25%
Medicine and Dentistry
Protein Kinase B
100%
Melanoma
100%
Neoplasm
40%
Xenograft
40%
Prostate Cell Line
40%
Melanoma Cell Line
40%
Breast Cell Line
40%
Signal Transduction
20%
Warfarin
20%
Nuclear Factor Kappa B
20%
phosphorylation
20%
Pharmacology, Toxicology and Pharmaceutical Science
Structure Activity Relationship
100%
Protein Kinase B
100%
Melanoma
100%
Neoplasm
33%
Warfarin
16%
Nuclear Factor
16%
Biochemistry, Genetics and Molecular Biology
Protein Kinase B
100%
Structure Activity Relationship
100%
Signal Transduction
20%
AKT1
20%
Nuclear Factor Kappa B
20%
phosphorylation
20%