Synthesis and preliminary biological evaluation of potent and selective 2-(3-alkoxy-1-azetidinyl) quinolines as novel PDE10A inhibitors with improved solubility

Robert M. Rzasa, Michael J. Frohn, Kristin L. Andrews, Samer Chmait, Ning Chen, Jeffrey G. Clarine, Carl Davis, Heather A. Eastwood, Daniel B. Horne, Essa Hu, Adrie D. Jones, Matthew R. Kaller, Roxanne K. Kunz, Silke Miller, Holger Monenschein, Thomas Nguyen, Alexander J. Pickrell, Amy Porter, Andreas Reichelt, Xiaoning ZhaoJames J.S. Treanor, Jennifer R. Allen

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18 Scopus citations

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Pharmacology, Toxicology and Pharmaceutical Science