Syneresis of vitreous by carbon dioxide laser radiation

T. J. Bridges, C. K.N. Patel, A. R. Strnad, O. R. Wood, E. S. Brewer, D. B. Karlin

Research output: Contribution to journalArticlepeer-review

10 Scopus citations


In carbon dioxide laser surgery of the vitreous a process of vaporization has been advocated. In this report syneresis, a thermal liquefaction of gel, is shown to be over ten times more efficient on an energy basis than vaporization. Syneresis of vitreous is experimentally shown to be a first-order kinetic process with an activation energy of 41 ± 0.5 kilocalories per mole. A theory of laser surgery in which this figure is used agrees closely with results from laser experiments on human eye-bank vitreous. The syneresis of vitreous by carbon dioxide laser radiation could lead to a more delicate form of ocular microsurgery, and application to other biological systems may be possible.

Original languageEnglish
Pages (from-to)1217-1219
Number of pages3
Issue number4589
StatePublished - 1983
Externally publishedYes


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