Synchrony in telomere length of the human fetus

Kjell Youngren, Elisabeth Jeanclos, Hana Aviv, Masayuki Kimura, Jeffrey Stock, Moneer Hanna, Joan Skurnick, Arlene Bardeguez, Abraham Aviv

Research output: Contribution to journalArticlepeer-review

110 Scopus citations

Abstract

Telomere length, measured by terminal restriction fragments, was examined in tissues from human fetuses of gestational ages estimated as 15-19 weeks. The length of telomeres was similar in most fetal tissues. However, there were significant variations in telomere length among fetuses, with no apparent relationship between gestational age and telomere length. We conclude that synchrony in telomere length exists among tissues of the human fetus. This synchrony is apparently lost during extrauterine life.

Original languageEnglish
Pages (from-to)640-643
Number of pages4
JournalHuman Genetics
Volume102
Issue number6
DOIs
StatePublished - 1998
Externally publishedYes

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