TY - JOUR
T1 - Synchronous lingual granular cell tumor and squamous carcinoma
T2 - A case report and review of the literature
AU - Said-Al-Naief, Nasser
AU - Brandwein, Margaret
AU - Lawson, William
AU - Gordon, Ronald
AU - Lumerman, Harry
PY - 1997/5
Y1 - 1997/5
N2 - Granular cell tumor (GCT) is a benign lesion with a preference for subcutaneous sites. Marked pseudoepitheliomatous hyperplasia, seen in 10% of GCTs, might be misdiagnosed as squamous cell carcinoma (SCC), and GCT in the oral tissues has been referred to as a medical curiosity in the literature. We report the clinicopathologic, immunohistochemical, and ultrastructural findings in a case of coexistent SCC and GCT in the tongue. There is no evidence in this case that suggests malignant transition of the GCT to carcinoma. To the best of our knowledge, this is the first report of synchronous GCT and SCC in the oral cavity.
AB - Granular cell tumor (GCT) is a benign lesion with a preference for subcutaneous sites. Marked pseudoepitheliomatous hyperplasia, seen in 10% of GCTs, might be misdiagnosed as squamous cell carcinoma (SCC), and GCT in the oral tissues has been referred to as a medical curiosity in the literature. We report the clinicopathologic, immunohistochemical, and ultrastructural findings in a case of coexistent SCC and GCT in the tongue. There is no evidence in this case that suggests malignant transition of the GCT to carcinoma. To the best of our knowledge, this is the first report of synchronous GCT and SCC in the oral cavity.
UR - http://www.scopus.com/inward/record.url?scp=0031009368&partnerID=8YFLogxK
U2 - 10.1001/archotol.1997.01900050099013
DO - 10.1001/archotol.1997.01900050099013
M3 - Article
C2 - 9158404
AN - SCOPUS:0031009368
SN - 0886-4470
VL - 123
SP - 543
EP - 547
JO - Archives of Otolaryngology - Head and Neck Surgery
JF - Archives of Otolaryngology - Head and Neck Surgery
IS - 5
ER -