TY - JOUR
T1 - Swine influenza viruses isolated in 1983, 2002 and 2009 in Sweden exemplify different lineages
AU - Kiss, István
AU - Bálint, Ádám
AU - Metreveli, Giorgi
AU - Emmoth, Eva
AU - Widén, Frederik
AU - Belák, Sándor
AU - Wallgren, Per
N1 - Funding Information:
Thanks are due to Attila Farsang for helpful discussions. This work was supported by an internal grant of the National Veterinary Institute, Uppsala, Sweden, by the Swedish Emergency Management Agency, the EPIZONE project (Network of Excellence for Epizootic Disease Diagnosis and Control, FP6-2004-Food-3-A), the Swedish Research Council for Environment, Agricultural Sciences and Spatial Planning (Formas 221-2006-2169 and Formas 221-2007-935) projects, the FLUTEST EU project (Contract No.: 044429) and by the Award of Excellence (Excellensbidrag) provided to SB by the Swedish University of Agricultural Sciences (SLU).
PY - 2010/11/14
Y1 - 2010/11/14
N2 - Swine influenza virus isolates originating from outbreaks in Sweden from 1983, 2002 and 2009 were subjected to nucleotide sequencing and phylogenetic analysis. The aim of the studies was to obtain an overview on their potential relatedness as well as to provide data for broader scale studies on swine influenza epidemiology. Nonetheless, analyzing archive isolates is justified by the efforts directed to the comprehension of the appearance of pandemic H1N1 influenza virus. Interestingly, this study illustrates the evolution of swine influenza viruses in Europe, because the earliest isolate belonged to 'classical' swine H1N1, the subsequent ones to Eurasian 'avian-like' swine H1N1 and reassortant 'avian-like' swine H1N2 lineages, respectively. The latter two showed close genetic relatedness regarding their PB2, HA, NP, and NS genes, suggesting common ancestry. The study substantiates the importance of molecular surveillance for swine influenza viruses.
AB - Swine influenza virus isolates originating from outbreaks in Sweden from 1983, 2002 and 2009 were subjected to nucleotide sequencing and phylogenetic analysis. The aim of the studies was to obtain an overview on their potential relatedness as well as to provide data for broader scale studies on swine influenza epidemiology. Nonetheless, analyzing archive isolates is justified by the efforts directed to the comprehension of the appearance of pandemic H1N1 influenza virus. Interestingly, this study illustrates the evolution of swine influenza viruses in Europe, because the earliest isolate belonged to 'classical' swine H1N1, the subsequent ones to Eurasian 'avian-like' swine H1N1 and reassortant 'avian-like' swine H1N2 lineages, respectively. The latter two showed close genetic relatedness regarding their PB2, HA, NP, and NS genes, suggesting common ancestry. The study substantiates the importance of molecular surveillance for swine influenza viruses.
UR - https://www.scopus.com/pages/publications/79551575441
U2 - 10.1186/1751-0147-52-65
DO - 10.1186/1751-0147-52-65
M3 - Article
C2 - 21156041
AN - SCOPUS:79551575441
SN - 0044-605X
VL - 52
JO - Acta Veterinaria Scandinavica
JF - Acta Veterinaria Scandinavica
IS - 1
M1 - 65
ER -