Sustained virologic response with short-course ribavirin and peginterferon treatment in 2 patients coinfected with HIV and HCV genotype 1

Mitesh R. Patel; Michael P. Mullen; Douglas T. Dieterich

Sustained virologic response with short-course ribavirin and peginterferon treatment in 2 patients coinfected with HIV and HCV genotype 1

Mitesh R. Patel, Michael P. Mullen, Douglas T. Dieterich

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

The current recommendation for the duration of treatment of patients infected with chronic hepatitis C virus(HCV)genotype 1 is 48 weeks; however, the standard regimen of peginterferon plus ribavirin bears significant adverse effects, which make completion of treatment exceedingly difficult. Reported here are 2 cases ofHIV- HCV-coinfected genotype-1 patients who discontinued treatment early(after 3 and 8 weeks)because of adverse effects yet had a sustained virologic response with undetectable HCV viral loads at follow-up.

Original language	English
Pages (from-to)	164-168-169
Journal	AIDS Reader
Volume	16
Issue number	3
State	Published - Mar 2006
Externally published	Yes

Keywords

HIV/AIDS
Hepatitis C
Hepatitis C Virus genotype 1
Peginterferon
Ribavirin

Cite this

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title = "Sustained virologic response with short-course ribavirin and peginterferon treatment in 2 patients coinfected with HIV and HCV genotype 1",

abstract = "The current recommendation for the duration of treatment of patients infected with chronic hepatitis C virus(HCV)genotype 1 is 48 weeks; however, the standard regimen of peginterferon plus ribavirin bears significant adverse effects, which make completion of treatment exceedingly difficult. Reported here are 2 cases ofHIV- HCV-coinfected genotype-1 patients who discontinued treatment early(after 3 and 8 weeks)because of adverse effects yet had a sustained virologic response with undetectable HCV viral loads at follow-up.",

keywords = "HIV/AIDS, Hepatitis C, Hepatitis C Virus genotype 1, Peginterferon, Ribavirin",

author = "Patel, \{Mitesh R.\} and Mullen, \{Michael P.\} and Dieterich, \{Douglas T.\}",

year = "2006",

month = mar,

language = "English",

volume = "16",

pages = "164--168--169",

journal = "AIDS Reader",

issn = "1053-0894",

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T1 - Sustained virologic response with short-course ribavirin and peginterferon treatment in 2 patients coinfected with HIV and HCV genotype 1

AU - Patel, Mitesh R.

AU - Mullen, Michael P.

AU - Dieterich, Douglas T.

PY - 2006/3

Y1 - 2006/3

N2 - The current recommendation for the duration of treatment of patients infected with chronic hepatitis C virus(HCV)genotype 1 is 48 weeks; however, the standard regimen of peginterferon plus ribavirin bears significant adverse effects, which make completion of treatment exceedingly difficult. Reported here are 2 cases ofHIV- HCV-coinfected genotype-1 patients who discontinued treatment early(after 3 and 8 weeks)because of adverse effects yet had a sustained virologic response with undetectable HCV viral loads at follow-up.

AB - The current recommendation for the duration of treatment of patients infected with chronic hepatitis C virus(HCV)genotype 1 is 48 weeks; however, the standard regimen of peginterferon plus ribavirin bears significant adverse effects, which make completion of treatment exceedingly difficult. Reported here are 2 cases ofHIV- HCV-coinfected genotype-1 patients who discontinued treatment early(after 3 and 8 weeks)because of adverse effects yet had a sustained virologic response with undetectable HCV viral loads at follow-up.

KW - HIV/AIDS

KW - Hepatitis C

KW - Hepatitis C Virus genotype 1

KW - Peginterferon

KW - Ribavirin

UR - https://www.scopus.com/pages/publications/33646003874

M3 - Article

C2 - 16538956

AN - SCOPUS:33646003874

SN - 1053-0894

VL - 16

SP - 164-168-169

JO - AIDS Reader

JF - AIDS Reader

IS - 3

ER -

Sustained virologic response with short-course ribavirin and peginterferon treatment in 2 patients coinfected with HIV and HCV genotype 1

Abstract

Keywords

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