Surgical resection for hepatocellular carcinoma in the noncirrhotic: The Western experience

Myron E. Schwartz, Brian Shrager

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

8 Scopus citations


Although hepatocellular carcinoma (HCC) is most often a sequela of severe hepatic fibrosis or cirrhosis, a proportion of cases arise in the noncirrhotic patient. The gold standard therapy in such cases is surgical resection. Innovations in operative technique allow for this treatment to be implemented with very low mortality and acceptable morbidity at high-volume hepatobiliary centers. This chapter discusses various etiologies of noncirrhotic HCC and presents a large single-center experience that is compared to other Western series.

Original languageEnglish
Title of host publicationMultidisciplinary Treatment of Hepatocellular Carcinoma
EditorsJean-Nicolas Vauthey, Antoine Brouquet
Number of pages16
StatePublished - 2013

Publication series

NameRecent Results in Cancer Research
ISSN (Print)0080-0015


  • Anatomic resection
  • Fibrosis
  • Hepatitis B virus
  • Hepatitis C virus
  • Hepatocellular carcinoma
  • Low-central venous pressure anesthesia
  • Multinodularity
  • Nonalcoholic steatohepatitis
  • Noncirrhotic
  • Portal vein embolization
  • Pringle maneuver
  • Radiofrequency ablation
  • Resection
  • Satellite nodules
  • Serum alpha-fetoprotein
  • Sorafenib
  • Transarterial chemoembolization
  • Vascular invasion


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