Surgery Approaches in Mesothelioma

Andrea Wolf, Raja Flores

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


The role of surgical resection in malignant pleural mesothelioma (MPM) is controversial, but cancer-directed surgery has yielded long-term survivors and demonstrated 15% 5-year survival. The two operations developed for surgical resection, extrapleural pneumonectomy (EPP), and radical or extended pleurectomy/decortication (P/D) are described. In addition, this chapter summarizes the preoperative, perioperative, and postoperative management of these patients and the results of studies evaluating both procedures. Data and clinical experience suggest that P/D is better tolerated by patients, and evidence suggests survival is not worse. Although EPP is still performed in selected cases, the authors advocate radical P/D for most patients with MPM.

Original languageEnglish
Title of host publicationCurrent Cancer Research
PublisherSpringer Nature
Number of pages16
StatePublished - 2017

Publication series

NameCurrent Cancer Research
ISSN (Print)2199-2584
ISSN (Electronic)2199-2592


  • Extrapleural pneumonectomy
  • Malignant pleural mesothelioma
  • Pleurectomy/decortication
  • Surgical resection


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