TY - JOUR
T1 - Surgery and cancer of the pancreas
T2 - Will common sense become common practice?
AU - Cooperman, Avram M.
AU - Fader, Andrew
AU - Cushin, Brian
AU - Golier, Francis
AU - Feld, Michael
AU - Kasmin, Franklin
AU - Cohen, Seth
AU - Mahadevia, Panna
AU - Shah, Kumudini
PY - 2002
Y1 - 2002
N2 - Pancreatic cancer is a systemic disease for most patients. Operations with the intent to cure may be done safely (mortality, <3%) with shorter hospital stays. Surgery has been minimally effective as a long-term cure. Endoscopic palliation of jaundice is becoming standard practice. Common sense dictates a defined and clear role for surgery (i.e., strict patient selection criteria). Surgery is of great value for small, localized lesions; of clear value as palliative therapy when nonoperative measures fail; and perhaps best applied after neoadjuvant chemoradiotherapy. Surgery is just part of the armamentarium available to treat pancreatic cancer. Novel systemic therapies, including chemotherapy, immunotherapy, and so-called targeted therapies, are becoming increasingly valuable in the management of this systemic disease and are discussed in detail in other articles in this issue.
AB - Pancreatic cancer is a systemic disease for most patients. Operations with the intent to cure may be done safely (mortality, <3%) with shorter hospital stays. Surgery has been minimally effective as a long-term cure. Endoscopic palliation of jaundice is becoming standard practice. Common sense dictates a defined and clear role for surgery (i.e., strict patient selection criteria). Surgery is of great value for small, localized lesions; of clear value as palliative therapy when nonoperative measures fail; and perhaps best applied after neoadjuvant chemoradiotherapy. Surgery is just part of the armamentarium available to treat pancreatic cancer. Novel systemic therapies, including chemotherapy, immunotherapy, and so-called targeted therapies, are becoming increasingly valuable in the management of this systemic disease and are discussed in detail in other articles in this issue.
UR - http://www.scopus.com/inward/record.url?scp=0036262497&partnerID=8YFLogxK
U2 - 10.1016/S0889-8588(01)00011-9
DO - 10.1016/S0889-8588(01)00011-9
M3 - Review article
C2 - 12063830
AN - SCOPUS:0036262497
SN - 0889-8588
VL - 16
SP - 81
EP - 94
JO - Hematology/Oncology Clinics of North America
JF - Hematology/Oncology Clinics of North America
IS - 1
ER -