Supratentorial recurrences in medulloblastoma

Berta Jereb, Narayan Sundaresan, Bruce Horten, Ann Reid, Joseph H. Galicich

Research output: Contribution to journalArticlepeer-review

43 Scopus citations


Four children with medulloblastoma had massive supratentorial recurrences in the region of the cribriform plate after adequate craniospinal irradiation. The pathogenesis of these recurrences is probably related to underdosage to this region caused by shielding of the eyes. This hypothesis was corroborated by autopsy findings in two other patients in whom subfrontal implants were histologically different from recurrences elsewhere. Two possible solutions to avoid this problem in the future are suggested.

Original languageEnglish
Pages (from-to)806-809
Number of pages4
Issue number4
StatePublished - 15 Feb 1981
Externally publishedYes


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