Abstract
A 59-year-old patient presented with marked cognitive impairment. Examination revealed supranuclear gaze palsy and ocular oscillations (video at Neurology.org). Extremity and axial muscle tone was increased, accompanied by full body tremulousness suggestive of polymyoclonus. Motor abnormalities had progressed over 3 months but cognitive problems developed in 1-2 weeks. MRI (figure) and CSF (positive real-time quaking-induced conversion) were diagnostic of Creutzfeldt-Jacob disease (CJD).
| Original language | English |
|---|---|
| Pages (from-to) | 749 |
| Number of pages | 1 |
| Journal | Neurology |
| Volume | 89 |
| Issue number | 7 |
| DOIs | |
| State | Published - 15 Aug 2017 |
| Externally published | Yes |
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