Supranuclear gaze palsy and horizontal ocular oscillations in Creutzfeldt-Jakob disease

Asya I. Wallach, Hannah Park, Janet C. Rucker, Horacio Kaufmann

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

A 59-year-old patient presented with marked cognitive impairment. Examination revealed supranuclear gaze palsy and ocular oscillations (video at Neurology.org). Extremity and axial muscle tone was increased, accompanied by full body tremulousness suggestive of polymyoclonus. Motor abnormalities had progressed over 3 months but cognitive problems developed in 1-2 weeks. MRI (figure) and CSF (positive real-time quaking-induced conversion) were diagnostic of Creutzfeldt-Jacob disease (CJD).

Original languageEnglish
Pages (from-to)749
Number of pages1
JournalNeurology
Volume89
Issue number7
DOIs
StatePublished - 15 Aug 2017
Externally publishedYes

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