Sujets métaboliquement sains, bien qu'obèses. Deuxième partie: Pronostic et prise en charge

N. Esser; N. Paquot; A. J. Scheen

doi:10.1007/s11690-009-0188-y

Sujets métaboliquement sains, bien qu'obèses. Deuxième partie: Pronostic et prise en charge

Translated title of the contribution: Metabolically Healthy, but Obese subjects. second part: Prognosis and management

N. Esser, N. Paquot, A. J. Scheen

Research output: Contribution to journal › Review article › peer-review

3 Scopus citations

Abstract

Approximately 30 to 50% of obese subjects are "Metabolically Healthy, but Obese" (MHO) whereas numerous non-obese subjects are "metabolically abnormal". The distribution and function of adipose depots seems to play a crucial role in explaining this apparent discrepancy. In a first paper, we described the clinical and biological characteristics of these MHO individuals, analyzing the underlying pathophysiological mechanisms, and reporting the prevalence of this syndrome in the adult population. This second paper aims at assessing the prognosis, especially with regard to the risk of diabetes and cardiovascular disease, and discussing the advantages and disadvantages of a classical therapeutic strategy for obesity among MHO individuals.

Translated title of the contribution	Metabolically Healthy, but Obese subjects. second part: Prognosis and management
Original language	French
Pages (from-to)	134-141
Number of pages	8
Journal	Obesite
Volume	4
Issue number	2
DOIs	https://doi.org/10.1007/s11690-009-0188-y
State	Published - Aug 2009
Externally published	Yes

Keywords

Cardiovascular disease
Diabetes
Metabolic syndrome
Metabolically healthy
Obesity
Treatment

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title = "Sujets m{\'e}taboliquement sains, bien qu'ob{\`e}ses. Deuxi{\`e}me partie: Pronostic et prise en charge",

abstract = "Approximately 30 to 50% of obese subjects are {"}Metabolically Healthy, but Obese{"} (MHO) whereas numerous non-obese subjects are {"}metabolically abnormal{"}. The distribution and function of adipose depots seems to play a crucial role in explaining this apparent discrepancy. In a first paper, we described the clinical and biological characteristics of these MHO individuals, analyzing the underlying pathophysiological mechanisms, and reporting the prevalence of this syndrome in the adult population. This second paper aims at assessing the prognosis, especially with regard to the risk of diabetes and cardiovascular disease, and discussing the advantages and disadvantages of a classical therapeutic strategy for obesity among MHO individuals.",

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AU - Paquot, N.

AU - Scheen, A. J.

PY - 2009/8

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N2 - Approximately 30 to 50% of obese subjects are "Metabolically Healthy, but Obese" (MHO) whereas numerous non-obese subjects are "metabolically abnormal". The distribution and function of adipose depots seems to play a crucial role in explaining this apparent discrepancy. In a first paper, we described the clinical and biological characteristics of these MHO individuals, analyzing the underlying pathophysiological mechanisms, and reporting the prevalence of this syndrome in the adult population. This second paper aims at assessing the prognosis, especially with regard to the risk of diabetes and cardiovascular disease, and discussing the advantages and disadvantages of a classical therapeutic strategy for obesity among MHO individuals.

AB - Approximately 30 to 50% of obese subjects are "Metabolically Healthy, but Obese" (MHO) whereas numerous non-obese subjects are "metabolically abnormal". The distribution and function of adipose depots seems to play a crucial role in explaining this apparent discrepancy. In a first paper, we described the clinical and biological characteristics of these MHO individuals, analyzing the underlying pathophysiological mechanisms, and reporting the prevalence of this syndrome in the adult population. This second paper aims at assessing the prognosis, especially with regard to the risk of diabetes and cardiovascular disease, and discussing the advantages and disadvantages of a classical therapeutic strategy for obesity among MHO individuals.

KW - Cardiovascular disease

KW - Diabetes

KW - Metabolic syndrome

KW - Metabolically healthy

KW - Obesity

KW - Treatment

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ER -

Sujets métaboliquement sains, bien qu'obèses. Deuxième partie: Pronostic et prise en charge

Abstract

Keywords

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