Sudden Cardiac Arrest in an Adult with Anomalous Origin of the Left Coronary Artery from the Pulmonary Artery (ALCAPA): Case Report

Francesca Romana Prandi, Ali N. Zaidi, Gina Larocca, Michael Hadley, Maria Riasat, Malcolm O. Anastasius, Pedro R. Moreno, Samin Sharma, Annapoorna Kini, Raghav Murthy, Percy Boateng, Stamatios Lerakis

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Introduction: Anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA) is a rare coronary artery anomaly that carries 90% mortality in the first year of life when left untreated. The diagnosis of ALCAPA is rare in adulthood, and it includes a broad spectrum of clinical manifestations, including sudden cardiac death (SCD). Case report: We report a rare case of resuscitated sudden cardiac arrest in a 55-year-old female, who was diagnosed with ALCAPA and underwent successful surgical correction and implantable cardioverter defibrillator (ICD) implantation for secondary prevention. Discussion: ALCAPA diagnosis is not confined to childhood, and it represents a rare cause of life-threatening arrhythmias and SCD in the adult population. Surgical correction is recommended, regardless of age, presence of symptoms or inducible myocardial ischemia. Multimodality imaging is crucial for diagnosis, management planning and follow up. Assessment of the risk of recurrent ventricular arrhythmias, despite full revascularization, should be performed in all adults with ALCAPA. Myocardial scar detected via late gadolinium enhancement represents a potential irreversible substrate for ventricular arrhythmias, and it provides additional information to evaluate indication of an ICD for secondary prevention.

Original languageEnglish
Article number1554
JournalInternational Journal of Environmental Research and Public Health
Issue number3
StatePublished - 1 Feb 2022


  • Anomalous origin of coronary artery from pulmonary artery
  • Cardiac arrest
  • Implantable cardioverter defibrillator
  • Multimodality cardiac imaging
  • Sudden cardiac death


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