TY - JOUR
T1 - Successful treatment of old world cutaneous leishmaniasis caused by Leishmania infantum with posaconazole
AU - Paniz Mondolfi, A. E.
AU - Stavropoulos, C.
AU - Gelanew, T.
AU - Loucas, E.
AU - Perez Alvarez, A. M.
AU - Benaim, G.
AU - Polsky, B.
AU - Schoenian, G.
AU - Sordillo, E. M.
PY - 2011/4
Y1 - 2011/4
N2 - Old World cutaneous leishmaniasis is a widespread and potentially disfiguring protozoal infection that is endemic in the Mediterranean basin, Africa, and parts of Asia. Human infection is caused by several species of Leishmania parasites, such as Leishmania infantum. Available systemic and topical treatments vary in efficacy and are often unjustified due to their toxicity. We report on a case that was treated with posaconazole, a drug typically considered an antifungal agent but which also targets specific metabolic pathways of the parasite.
AB - Old World cutaneous leishmaniasis is a widespread and potentially disfiguring protozoal infection that is endemic in the Mediterranean basin, Africa, and parts of Asia. Human infection is caused by several species of Leishmania parasites, such as Leishmania infantum. Available systemic and topical treatments vary in efficacy and are often unjustified due to their toxicity. We report on a case that was treated with posaconazole, a drug typically considered an antifungal agent but which also targets specific metabolic pathways of the parasite.
UR - http://www.scopus.com/inward/record.url?scp=79953213662&partnerID=8YFLogxK
U2 - 10.1128/AAC.01498-10
DO - 10.1128/AAC.01498-10
M3 - Article
C2 - 21282455
AN - SCOPUS:79953213662
SN - 0066-4804
VL - 55
SP - 1774
EP - 1776
JO - Antimicrobial Agents and Chemotherapy
JF - Antimicrobial Agents and Chemotherapy
IS - 4
ER -