Successful treatment of old world cutaneous leishmaniasis caused by Leishmania infantum with posaconazole

A. E. Paniz Mondolfi, C. Stavropoulos, T. Gelanew, E. Loucas, A. M. Perez Alvarez, G. Benaim, B. Polsky, G. Schoenian, E. M. Sordillo

Research output: Contribution to journalArticlepeer-review

46 Scopus citations

Abstract

Old World cutaneous leishmaniasis is a widespread and potentially disfiguring protozoal infection that is endemic in the Mediterranean basin, Africa, and parts of Asia. Human infection is caused by several species of Leishmania parasites, such as Leishmania infantum. Available systemic and topical treatments vary in efficacy and are often unjustified due to their toxicity. We report on a case that was treated with posaconazole, a drug typically considered an antifungal agent but which also targets specific metabolic pathways of the parasite.

Original languageEnglish
Pages (from-to)1774-1776
Number of pages3
JournalAntimicrobial Agents and Chemotherapy
Volume55
Issue number4
DOIs
StatePublished - Apr 2011

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