Abstract
A 56-year-old-man presented with syncope and torsades de pointes secondary to methadone-induced QT prolongation. After transition from methadone to buprenorphine, a partial μ-opiate-receptor agonist and a κ-opiate- receptor antagonist, the QT normalized and ventricular arrhythmias resolved. Buprenorphine should be used for opiate dependence and chronic pain in patients with methadone-induced QT prolongation and as first line therapy in patients with risk factors for torsades de pointes.
| Original language | English |
|---|---|
| Pages (from-to) | 117-119 |
| Number of pages | 3 |
| Journal | Journal of Interventional Cardiac Electrophysiology |
| Volume | 23 |
| Issue number | 2 |
| DOIs | |
| State | Published - Nov 2008 |
| Externally published | Yes |
Keywords
- Buprenorphine
- Methadone
- Prolonged QT
- Torsades de pointes
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