Subsurface structure of tissues investigated by noninvasive optical second harmonic tomography

Yici Guo, Howard E. Savage, Feng Liu, Stimson P. Schantz, P. P. Ho, R. R. Alfano

Research output: Contribution to journalConference articlepeer-review

6 Scopus citations

Abstract

Second harmonic imaging was used to evaluate the subsurface layer structure of hamster cheek pouch mucosal tissues using femtosecond laser technology. Two dimensional images of hamster cheek pouch mucosa were obtained by scanning the second harmonic signal at various lateral and axial positions. The spatial mapping of the second harmonic signals showed depth differentiation between different tissue layers.

Original languageEnglish
Pages (from-to)480-482
Number of pages3
JournalProceedings of SPIE - The International Society for Optical Engineering
Volume3597
StatePublished - 1999
Externally publishedYes
EventProceedings of the 1999 Optical Tomography and Spectroscopy of Tissue III - San Jose, CA, USA
Duration: 24 Jan 199928 Jan 1999

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