TY - JOUR
T1 - Striatal Syndrome Following Hyponatremia and Its Rapid Correction
T2 - A Manifestation of Extrapontine Myelinolysis Confirmed by Magnetic Resonance Imaging
AU - Dickoff, David J.
AU - Raps, Mitchell
AU - Yahr, Melvin D.
PY - 1988/1
Y1 - 1988/1
N2 - Several pathologic reports have indicated the occurrence of extrapontine sites of myelinosis associated with electrolyte disturbance and its rapid correction. Clinical evidence of the presence of such lesions, however, have rarely been described. We report a case of a 50-year-old man who following rapid correction of electrolyte imbalance developed a profound striatal syndrome. The clinical manifestations, the course of his illness as well as response to therapy, confirmation of lesion sites by magnetic resonance imaging (MRI), and abnormalities on visually evoked potentials are described in detail.
AB - Several pathologic reports have indicated the occurrence of extrapontine sites of myelinosis associated with electrolyte disturbance and its rapid correction. Clinical evidence of the presence of such lesions, however, have rarely been described. We report a case of a 50-year-old man who following rapid correction of electrolyte imbalance developed a profound striatal syndrome. The clinical manifestations, the course of his illness as well as response to therapy, confirmation of lesion sites by magnetic resonance imaging (MRI), and abnormalities on visually evoked potentials are described in detail.
UR - http://www.scopus.com/inward/record.url?scp=0023833212&partnerID=8YFLogxK
U2 - 10.1001/archneur.1988.00520250122033
DO - 10.1001/archneur.1988.00520250122033
M3 - Article
C2 - 3337664
AN - SCOPUS:0023833212
SN - 0003-9942
VL - 45
SP - 112
EP - 114
JO - Archives of Neurology
JF - Archives of Neurology
IS - 1
ER -