Keyphrases
Therapeutic Target
100%
Striatal
100%
Glutamatergic
100%
Gene Dysregulation
100%
Heroin Abusers
100%
H3K27 Acetylation
100%
Opiates
66%
Striatum
66%
Epigenetics
66%
Histone H3
66%
Heroin
66%
Lysine
66%
Drug Seeking
66%
Heroin Self-administration
66%
Chromatin Accessibility
66%
Hyperacetylation
66%
United States
33%
Human Brain
33%
In Vitro Model
33%
Brain Regions
33%
Postmortem Brain
33%
Neurobiology
33%
Transcriptional Profiling
33%
Molecular Insight
33%
Acetylated Histone H3
33%
Epigenetic Profiling
33%
Self-administration Model
33%
Chromatin Remodeling
33%
Use History
33%
Transcriptome
33%
Clinical Intervention
33%
Heroin Users
33%
Transcriptional Changes
33%
Cue-induced Drug Seeking
33%
Toxicology
33%
Glutamatergic Neurotransmission
33%
Addiction-like Behavior
33%
Gene Body
33%
Caucasian Population
33%
Bromodomain Inhibitors
33%
Heroin Use
33%
Acetylated Lysine
33%
Translational Model
33%
Opioid Overdose
33%
GRIA1
33%
Human Striatum
33%
Biochemical Experiment
33%
Opiate Abuse
33%
Heroin Use Disorder
33%
Functional Readouts
33%
Behavioral Insights
33%
Dynamic Correlation
33%
Neuroscience
Acetylation
100%
Heroin
100%
Striatum
37%
Histone H3
37%
Lysine
37%
Opiate
25%
Drug Seeking Behavior
25%
Behavior (Neuroscience)
12%
In Vitro
12%
Transcriptome
12%
Synaptic Transmission
12%
Chromatin Assembly and Disassembly
12%
Clinical Intervention
12%
GRIA1
12%
Bromodomain
12%
Opiate Abuse
12%
Neurobiology
12%