Strategies for treatment of dystonia

Dirk Dressler; Eckart Altenmueller; Roongroj Bhidayasiri; Saeed Bohlega; Pedro Chana; Tae Mo Chung; Steven Frucht; Pedro J. Garcia-Ruiz; Alain Kaelin; Ryuji Kaji; Petr Kanovsky; Rainer Laskawi; Federico Micheli; Olga Orlova; Maja Relja; Raymond Rosales; Jaroslaw Slawek; Sofia Timerbaeva; Thomas T. Warner; Fereshte Adib Saberi

doi:10.1007/s00702-015-1453-x

Strategies for treatment of dystonia

Dirk Dressler, Eckart Altenmueller, Roongroj Bhidayasiri, Saeed Bohlega, Pedro Chana, Tae Mo Chung, Steven Frucht, Pedro J. Garcia-Ruiz, Alain Kaelin, Ryuji Kaji, Petr Kanovsky, Rainer Laskawi, Federico Micheli, Olga Orlova, Maja Relja, Raymond Rosales, Jaroslaw Slawek, Sofia Timerbaeva, Thomas T. Warner, Fereshte Adib Saberi

Icahn School of Medicine at Mount Sinai

Research output: Contribution to journal › Review article › peer-review

29 Scopus citations

Abstract

Treatment of dystonias is generally symptomatic. To produce sufficient therapy effects, therefore, frequently a multimodal and interdisciplinary therapeutic approach becomes necessary, combining botulinum toxin therapy, deep brain stimulation, oral antidystonic drugs, adjuvant drugs and rehabilitation therapy including physiotherapy, occupational therapy, re-training, speech therapy, psychotherapy and sociotherapy. This review presents the recommendations of the IAB—Interdisciplinary Working Group for Movement Disorders Special Task Force on Interdisciplinary Treatment of Dystonia. It reviews the different therapeutic modalities and outlines a strategy to adapt them to the dystonia localisation and severity of the individual patient. Hints to emerging and future therapies will be given.

Original language	English
Pages (from-to)	251-258
Number of pages	8
Journal	Journal of Neural Transmission
Volume	123
Issue number	3
DOIs	https://doi.org/10.1007/s00702-015-1453-x
State	Published - 1 Mar 2016

Keywords

Antidystonic drugs
Botulinum toxin
Deep brain stimulation
Dystonia
Interdisciplinary approach
Multimodal therapies
Rehabilitation therapy
Treatment strategies

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10.1007/s00702-015-1453-x

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Dressler, D., Altenmueller, E., Bhidayasiri, R., Bohlega, S., Chana, P., Chung, T. M., Frucht, S., Garcia-Ruiz, P. J., Kaelin, A., Kaji, R., Kanovsky, P., Laskawi, R., Micheli, F., Orlova, O., Relja, M., Rosales, R., Slawek, J., Timerbaeva, S., Warner, T. T., & Saberi, F. A. (2016). Strategies for treatment of dystonia. Journal of Neural Transmission, 123(3), 251-258. https://doi.org/10.1007/s00702-015-1453-x

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title = "Strategies for treatment of dystonia",

abstract = "Treatment of dystonias is generally symptomatic. To produce sufficient therapy effects, therefore, frequently a multimodal and interdisciplinary therapeutic approach becomes necessary, combining botulinum toxin therapy, deep brain stimulation, oral antidystonic drugs, adjuvant drugs and rehabilitation therapy including physiotherapy, occupational therapy, re-training, speech therapy, psychotherapy and sociotherapy. This review presents the recommendations of the IAB—Interdisciplinary Working Group for Movement Disorders Special Task Force on Interdisciplinary Treatment of Dystonia. It reviews the different therapeutic modalities and outlines a strategy to adapt them to the dystonia localisation and severity of the individual patient. Hints to emerging and future therapies will be given.",

keywords = "Antidystonic drugs, Botulinum toxin, Deep brain stimulation, Dystonia, Interdisciplinary approach, Multimodal therapies, Rehabilitation therapy, Treatment strategies",

author = "Dirk Dressler and Eckart Altenmueller and Roongroj Bhidayasiri and Saeed Bohlega and Pedro Chana and Chung, {Tae Mo} and Steven Frucht and Garcia-Ruiz, {Pedro J.} and Alain Kaelin and Ryuji Kaji and Petr Kanovsky and Rainer Laskawi and Federico Micheli and Olga Orlova and Maja Relja and Raymond Rosales and Jaroslaw Slawek and Sofia Timerbaeva and Warner, {Thomas T.} and Saberi, {Fereshte Adib}",

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year = "2016",

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doi = "10.1007/s00702-015-1453-x",

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Dressler, D, Altenmueller, E, Bhidayasiri, R, Bohlega, S, Chana, P, Chung, TM, Frucht, S, Garcia-Ruiz, PJ, Kaelin, A, Kaji, R, Kanovsky, P, Laskawi, R, Micheli, F, Orlova, O, Relja, M, Rosales, R, Slawek, J, Timerbaeva, S, Warner, TT & Saberi, FA 2016, 'Strategies for treatment of dystonia', Journal of Neural Transmission, vol. 123, no. 3, pp. 251-258. https://doi.org/10.1007/s00702-015-1453-x

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AU - Dressler, Dirk

AU - Altenmueller, Eckart

AU - Bhidayasiri, Roongroj

AU - Bohlega, Saeed

AU - Chana, Pedro

AU - Chung, Tae Mo

AU - Frucht, Steven

AU - Garcia-Ruiz, Pedro J.

AU - Kaelin, Alain

AU - Kaji, Ryuji

AU - Kanovsky, Petr

AU - Laskawi, Rainer

AU - Micheli, Federico

AU - Orlova, Olga

AU - Relja, Maja

AU - Rosales, Raymond

AU - Slawek, Jaroslaw

AU - Timerbaeva, Sofia

AU - Warner, Thomas T.

AU - Saberi, Fereshte Adib

PY - 2016/3/1

Y1 - 2016/3/1

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AB - Treatment of dystonias is generally symptomatic. To produce sufficient therapy effects, therefore, frequently a multimodal and interdisciplinary therapeutic approach becomes necessary, combining botulinum toxin therapy, deep brain stimulation, oral antidystonic drugs, adjuvant drugs and rehabilitation therapy including physiotherapy, occupational therapy, re-training, speech therapy, psychotherapy and sociotherapy. This review presents the recommendations of the IAB—Interdisciplinary Working Group for Movement Disorders Special Task Force on Interdisciplinary Treatment of Dystonia. It reviews the different therapeutic modalities and outlines a strategy to adapt them to the dystonia localisation and severity of the individual patient. Hints to emerging and future therapies will be given.

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KW - Botulinum toxin

KW - Deep brain stimulation

KW - Dystonia

KW - Interdisciplinary approach

KW - Multimodal therapies

KW - Rehabilitation therapy

KW - Treatment strategies

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VL - 123

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EP - 258

JO - Journal of Neural Transmission

JF - Journal of Neural Transmission

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ER -

Strategies for treatment of dystonia

Abstract

Keywords

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