@inproceedings{163af66469db4aa39ad46c3f80c787fd,
title = "Stochastic modeling of cytoplasmic reactions in complex biological systems",
abstract = "The use of {"}in silico{"} stochastic event based modeling can identify the dynamic interactions of different processes in a complex biological system. This requires the computation of the time taken by different events in the system based on their biological functions. One such important event is the reactions between the molecules inside the cytoplasm of a cell. We present a mathematical formulation for the estimation of the reaction time between two molecules within a cell based on the system state. We derive expressions for the average and second moment of the time for reaction to be used by our stochastic event-based simulation. Unlike rate equations, the proposed model does not require the assumption of concentration stability for multiple molecule reactions.",
author = "Preetam Ghosh and Samik Ghosh and Kalyan Basu and Sajal Das and Simon Daefler",
year = "2006",
doi = "10.1007/11751540_60",
language = "English",
isbn = "354034070X",
series = "Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)",
publisher = "Springer Verlag",
pages = "566--576",
booktitle = "Computational Science and Its Applications - ICCSA 2006",
address = "Germany",
note = "ICCSA 2006: International Conference on Computational Science and Its Applications ; Conference date: 08-05-2006 Through 11-05-2006",
}