Abstract
The first naturally occurring anhydrophytosphingosine, pachastrissamine (jaspine B), a marine compound cytotoxic toward P388, A549, HT29, and MEL28 cell lines at IC50 = 0.01 μg/mL level, has been stereoselectively synthesized from D-xylose in 10 linear steps with 25.7% overall yield.
Original language | English |
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Pages (from-to) | 1251-1253 |
Number of pages | 3 |
Journal | Journal of Organic Chemistry |
Volume | 71 |
Issue number | 3 |
DOIs | |
State | Published - 3 Feb 2006 |
Externally published | Yes |