Statistical modelling of the determinants of historical exposure to bitumen and polycyclic aromatic hydrocarbons among paving workers

Igor Burstyn; Hans Kromhout; Timo Kauppinen; Pirjo Heikkila; Paolo Boffetta

doi:10.1016/S0003-4878(99)00101-5

Statistical modelling of the determinants of historical exposure to bitumen and polycyclic aromatic hydrocarbons among paving workers

Igor Burstyn, Hans Kromhout, Timo Kauppinen, Pirjo Heikkila, Paolo Boffetta

Research output: Contribution to journal › Article › peer-review

135 Scopus citations

Abstract

Introduction: An industrial hygiene database has been constructed for the exposure assessment in a study of cancer risk among asphalt workers.Aim: To create models of bitumen and polycyclic aromatic hydrocarbons (PAH) exposure intensity among paving workers.Methods: Individual exposure measurements from pavers (N=1581) were collected from 8 countries. Correlation patterns between exposure measures were examined and factors affecting exposure were identified using statistical modelling.Results: Inhalable dust appeared to be a good proxy of bitumen fume exposure. Bitumen fume and vapour levels were not correlated. Benzo(a)pyrene level appeared to be a good indicator of PAH exposure. All exposures steadily declined over the last 20 years. Mastic laying, re-paving, surface dressing, oil gravel paving and asphalt temperature were significant determinants of bitumen exposure. Coal tar use dictated PAH exposure levels.Discussion: Bitumen fume, vapour and PAH have different determinants of exposure. For paving workers, exposure intensity can be assessed on the basis of time period and production characteristics. Copyright (C) 2000 British Occupational Hygiene Society.

Original language	English
Pages (from-to)	43-56
Number of pages	14
Journal	Annals of Occupational Hygiene
Volume	44
Issue number	1
DOIs	https://doi.org/10.1016/S0003-4878(99)00101-5
State	Published - Jan 2000
Externally published	Yes

Keywords

Asphalt
Bitumen
Coal tar
Database
Determinants of exposure
Mastic
Multicentric study
Retrospective exposure assessment
Road construction

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10.1016/S0003-4878(99)00101-5

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title = "Statistical modelling of the determinants of historical exposure to bitumen and polycyclic aromatic hydrocarbons among paving workers",

abstract = "Introduction: An industrial hygiene database has been constructed for the exposure assessment in a study of cancer risk among asphalt workers.Aim: To create models of bitumen and polycyclic aromatic hydrocarbons (PAH) exposure intensity among paving workers.Methods: Individual exposure measurements from pavers (N=1581) were collected from 8 countries. Correlation patterns between exposure measures were examined and factors affecting exposure were identified using statistical modelling.Results: Inhalable dust appeared to be a good proxy of bitumen fume exposure. Bitumen fume and vapour levels were not correlated. Benzo(a)pyrene level appeared to be a good indicator of PAH exposure. All exposures steadily declined over the last 20 years. Mastic laying, re-paving, surface dressing, oil gravel paving and asphalt temperature were significant determinants of bitumen exposure. Coal tar use dictated PAH exposure levels.Discussion: Bitumen fume, vapour and PAH have different determinants of exposure. For paving workers, exposure intensity can be assessed on the basis of time period and production characteristics. Copyright (C) 2000 British Occupational Hygiene Society.",

keywords = "Asphalt, Bitumen, Coal tar, Database, Determinants of exposure, Mastic, Multicentric study, Retrospective exposure assessment, Road construction",

author = "Igor Burstyn and Hans Kromhout and Timo Kauppinen and Pirjo Heikkila and Paolo Boffetta",

note = "Funding Information: An IARC Special Training Award supported Igor Burstyn. The study was partially supported by a grant of the European Commission, DG-XII, Biomed-2 programme (Contract No. BMH4-CT95-1100), European industrial associations, EAPA, Eurobitume and CONCAWE. Pamela Cruise edited the manuscript. Wim Braun created SAS programs used in investigating the stability of models. Chava Perez provided valuable comments on the final manuscript.",

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AU - Burstyn, Igor

AU - Kromhout, Hans

AU - Kauppinen, Timo

AU - Heikkila, Pirjo

AU - Boffetta, Paolo

N1 - Funding Information: An IARC Special Training Award supported Igor Burstyn. The study was partially supported by a grant of the European Commission, DG-XII, Biomed-2 programme (Contract No. BMH4-CT95-1100), European industrial associations, EAPA, Eurobitume and CONCAWE. Pamela Cruise edited the manuscript. Wim Braun created SAS programs used in investigating the stability of models. Chava Perez provided valuable comments on the final manuscript.

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N2 - Introduction: An industrial hygiene database has been constructed for the exposure assessment in a study of cancer risk among asphalt workers.Aim: To create models of bitumen and polycyclic aromatic hydrocarbons (PAH) exposure intensity among paving workers.Methods: Individual exposure measurements from pavers (N=1581) were collected from 8 countries. Correlation patterns between exposure measures were examined and factors affecting exposure were identified using statistical modelling.Results: Inhalable dust appeared to be a good proxy of bitumen fume exposure. Bitumen fume and vapour levels were not correlated. Benzo(a)pyrene level appeared to be a good indicator of PAH exposure. All exposures steadily declined over the last 20 years. Mastic laying, re-paving, surface dressing, oil gravel paving and asphalt temperature were significant determinants of bitumen exposure. Coal tar use dictated PAH exposure levels.Discussion: Bitumen fume, vapour and PAH have different determinants of exposure. For paving workers, exposure intensity can be assessed on the basis of time period and production characteristics. Copyright (C) 2000 British Occupational Hygiene Society.

AB - Introduction: An industrial hygiene database has been constructed for the exposure assessment in a study of cancer risk among asphalt workers.Aim: To create models of bitumen and polycyclic aromatic hydrocarbons (PAH) exposure intensity among paving workers.Methods: Individual exposure measurements from pavers (N=1581) were collected from 8 countries. Correlation patterns between exposure measures were examined and factors affecting exposure were identified using statistical modelling.Results: Inhalable dust appeared to be a good proxy of bitumen fume exposure. Bitumen fume and vapour levels were not correlated. Benzo(a)pyrene level appeared to be a good indicator of PAH exposure. All exposures steadily declined over the last 20 years. Mastic laying, re-paving, surface dressing, oil gravel paving and asphalt temperature were significant determinants of bitumen exposure. Coal tar use dictated PAH exposure levels.Discussion: Bitumen fume, vapour and PAH have different determinants of exposure. For paving workers, exposure intensity can be assessed on the basis of time period and production characteristics. Copyright (C) 2000 British Occupational Hygiene Society.

KW - Asphalt

KW - Bitumen

KW - Coal tar

KW - Database

KW - Determinants of exposure

KW - Mastic

KW - Multicentric study

KW - Retrospective exposure assessment

KW - Road construction

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Statistical modelling of the determinants of historical exposure to bitumen and polycyclic aromatic hydrocarbons among paving workers

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